112616-81-6

Basic information

• Product Name: Furan, 2-(2-nitro-1-phenylethyl)-
• CAS NO: 112616-81-6
• Molecular Formula: C12H11NO3
• Molecular Weight: 217.224
• Mol File: 112616-81-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Furan, 2-(2-nitro-1-phenylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Furan, 2-(2-nitro-1-phenylethyl)-(112616-81-6)
• EPA Substance Registry System: Furan, 2-(2-nitro-1-phenylethyl)-(112616-81-6)

Safety Data

• Hazardous Substances Data: 112616-81-6(Hazardous Substances Data)

Upstream product

• 110-00-9 furan 
• 5153-67-3 nitrostyrene 
• 699-18-3 2-[(E)-2-nitroethenyl]furan 
• 595-90-4 tetraphenyltin(IV) 
• 102-96-5 (2-nitroethenyl)benzene 
• 699-18-3 2-(2-nitrovinyl)furan 

Downstream Products

• 135589-75-2 (E/Z)-2-(2-nitro-1-phenylethen-1-yl)furan 

Relevant articles and documents

Lithium perchlorate accelerated Friedel-Crafts addition of furans to β-nitrostyrenes

The Friedel-Crafts alkylation of furans by the Michael acceptor, β-nitrostyrene, is greatly accelerated by the use of the Lewis acid catalyst and solvent, 5 M lithium perchlorate in diethyl ether (LDPE).

Palladium(II)-catalyzed Michael-type hydroarylation of nitroalkenes using aryltins and sodium tetraarylborates

A variety of aryltin compounds and sodium tetraarylborates can be employed for Michael-type hydroarylation reactions of nitroalkenes to afford β-arylnitroalkanes in moderate to good yields in the presence of either LiCl, MgCl2, or CaCl2 and a catalytic amount of palladium(II) salt (0.05 molar amount) in acetic acid. Results show that 50-70% of aryl groups out of all in these aryl compounds can be transferred to the products in this hydroarylation. The addition of a catalytic amount (0.05-0.10 molar amount) of a Lewis acid chloride, BiCl3 or SbCl3, much improves the product yield in some cases.