1126387-10-7Relevant articles and documents
PARACYCLOPHANE-BASED LIGANDS, THEIR PREPARATION AND USE IN CATALYSIS
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Page/Page column 10, (2009/04/25)
A substituted paracyclophane is described of formula (I) wherein X1 and X2 are linking groups comprising between 2 to 4 carbon atoms, Y1 and Y2 are selected from the group consisting of hydrogen, halide, oxygen, nitrogen, alkyl, cycloalkyl, aryl or heteroaryl and Z is a substituted or unsubstituted alkyl group, aryl group or heteroaryl group. Preferably X1 and X2 are -(C2H4)- and Z is a substituted aryl group. The substituted paracyclophane provides transition metal catalysts that are useful in C-C and C-N bond formation and asymmetric hydrogenation reactions.
Paracyclophane-based monophosphine ligand for palladium-catalyzed cross-coupling reactions of aryl chlorides
Ruan, Jiwu,Shearer, Lee,Mo, Jun,Bacsa, John,Zanotti-Gerosa, Antonio,Hancock, Fred,Wu, Xiaofeng,Xiao, Jianliang
experimental part, p. 3236 - 3242 (2009/10/23)
A new [2.2]paracyclophane-based electron-rich and sterically bulky monophosphine ligand has been synthesized by an efficient and straightforward method. When combined with palladium, this ligand shows excellent performance in the Buchwald-Hartwig amination and Suzuki-Miyaura coupling reactions of various aryl chlorides. In both types of reactions, ortho-substituted, deactivated aryl chlorides are shown to be viable substrates. However, the Suzuki-Miyaura coupling appears to be easier, with palladium loading at 0.1 mol% being feasible. The Royal Society of Chemistry 2009.
