112641-97-1Relevant academic research and scientific papers
STERICALLY SCREENED HALOGENOCYCLOBUTANONES. II. TRANSFORMATION OF CYCLOPROPYL-SUBSTITUTED 2,2-DICHLOROCYCLOBUTANONES UNDER THE INFLUENCE OF SODIUM METHOXIDE
Donskaya, N. A.,Bessmertnykh, A. G.,Drobysh, V. A.,Shabarov, Yu. S.
, p. 676 - 680 (2007/10/02)
The reaction of cyclopropyl-substituted 2,2-dichlorocyclobutanones (Ia-c) with sodium methoxide was studied.In the case of the 3,3-disubstituted cyclobutanones (Ib, c) and (VI) the only direction of reaction is substitution of the chlorine atoms with the formation of the corresponding 2,2-dimethoxycyclobutanones.From 2,2-dichloro-3-cyclopropylcyclobutanone both the substitution product 2,2-dimethoxy-3-cyclopropylcyclobutanone and the ring opening product, i.e., the corresponding dichlorobutyric acid, are obtained.
