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112642-02-1

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112642-02-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 112642-02-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,6,4 and 2 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 112642-02:
(8*1)+(7*1)+(6*2)+(5*6)+(4*4)+(3*2)+(2*0)+(1*2)=81
81 % 10 = 1
So 112642-02-1 is a valid CAS Registry Number.
InChI:InChI=1/C24H28O2/c1-16(14-18-8-6-7-9-19(18)22(25)26)17-10-11-20-21(15-17)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14+

112642-02-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[(E)-2-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)prop-1-enyl]benzoic acid

1.2 Other means of identification

Product number -
Other names Benzoic aicd,2-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)-,(E)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:112642-02-1 SDS

112642-02-1Downstream Products

112642-02-1Relevant articles and documents

Programmed cell death (PCD) associated with the stilbene motif of arotinoids: Discovery of novel apoptosis inducer agents possessing activity on multidrug resistant tumor cells

Simoni, Daniele,Roberti, Marinella,Paolo Invidiata, Francesco,Rondanin, Riccardo,Baruchello, Riccardo,Malagutti, Cinzia,Mazzali, Angelica,Rossi, Marcello,Grimaudo, Stefania,Dusonchet, Luisa,Meli, Maria,Raimondi, Maria Valeria,D'Alessandro, Natale,Tolomeo, Manlio

, p. 2669 - 2673 (2007/10/03)

Considering that the stereochemistry of the C9-C10 alkenyl portion of natural 9-cis-RA, as the one of the olefinic moiety of the previously described isoxazole retinoid 4, seems of particular importance for their apoptotic activity, we prepared a novel class of TTNPB analogues bearing both the cis or trans configuration of the alkenyl portion. The compounds were evaluated in vitro for their cytotoxic and apoptotic activities. We discovered that the cis-TTNPB 9c possesses apoptotic activity comparable with that of the retinoid 4. Moreover, the amino arotinoid 16c showed potent apoptotic activity in HL60 promyelocytic leukemia cells. Interestingly, 16c proved to be a particularly potent apoptosis-inducing agent active in multidrug resistant (MDR) cell lines. Therefore, to the best of our knowledge, 16c may represent the first known aminoarotinoid endowed with potent apoptotic activity in MDR cells. Taken together, these results seem to point out that the cis-stilbene motif of arotinoids may be at least an important feature in conferring cytotoxic and apoptotic activity to this class of compounds. (C) 2000 Elsevier Science Ltd.

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