1126425-92-0

Basic information

• Product Name: 2-chloro-6-(4-chloro-1-(triisopropylsilyl)-1H-pyrrol-3-yl)aniline
• Synonyms: 2-chloro-6-(4-chloro-1-(triisopropylsilyl)-1H-pyrrol-3-yl)aniline
• CAS NO: 1126425-92-0
• Molecular Weight: 383.436
• Mol File: 1126425-92-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-chloro-6-(4-chloro-1-(triisopropylsilyl)-1H-pyrrol-3-yl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-6-(4-chloro-1-(triisopropylsilyl)-1H-pyrrol-3-yl)aniline(1126425-92-0)
• EPA Substance Registry System: 2-chloro-6-(4-chloro-1-(triisopropylsilyl)-1H-pyrrol-3-yl)aniline(1126425-92-0)

Safety Data

• Hazardous Substances Data: 1126425-92-0(Hazardous Substances Data)

Upstream product

• 13420-63-8 2-chloro-6-iodobenzoic acid 
• 84483-28-3 2-chloro-6-iodoaniline 
• 1126425-82-8 3-chloro-4-(4',4',5',5'-tetramethyl-1',3',2'-dioxaborolan-2'-yl)-N-(TIPS)pyrrole 
• 59772-49-5 2-bromo-6-chloroaniline 

Downstream Products

• 16386-65-5 4-(3'-chloro-2'-aminophenyl)-3-chloropyrrole 

Relevant articles and documents

Synthesis and Investigation of the Abiotic Formation of Pyonitrins A-D

Pyonitrins A-D are recently isolated natural products from the insect-associated Pseudomonas protegens strain, which were isolated from complex fractions that exhibited antifungal activity via an in vivo murine candidiasis assay. Genomic studies of Pseudomonas protegens suggested that pyonitrins A-D are formed via a spontaneous nonenzymatic reaction between biosynthetic intermediates of two well-known natural products pyochelin and pyrrolnitrin. Herein we have accomplished the first biomimetic total synthesis of pyonitrins A-D in three steps and studied the nonenzymatic formation of the pyonitrins using 15N NMR spectroscopy.