1126433-39-3 Usage
Uses
Used in Pharmaceutical Industry:
FMOC-Thr(tBu)-Bt is used as a building block for peptide synthesis, enabling the creation of custom-designed peptides with specific functionalities and properties. The FMOC group offers protection for the amino group of threonine, allowing for selective deprotection and coupling in peptide synthesis. This selective process is crucial for the development of new drugs and therapeutic agents.
Used in Research and Development:
In the field of research and development, FMOC-Thr(tBu)-Bt is utilized as a key component in the synthesis of novel peptides for various applications, including drug discovery, diagnostics, and therapeutics. The t-butyl and benzothiazole groups serve as additional protective and functional units, enhancing the compound's versatility and potential for innovative uses.
Used in Chemical Synthesis:
FMOC-Thr(tBu)-Bt is employed as a reagent in chemical synthesis processes, particularly for the production of complex organic molecules and bioactive compounds. Its unique structure and protective groups make it a valuable tool for chemists working on the development of new chemical entities and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 1126433-39-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,2,6,4,3 and 3 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1126433-39:
(9*1)+(8*1)+(7*2)+(6*6)+(5*4)+(4*3)+(3*3)+(2*3)+(1*9)=123
123 % 10 = 3
So 1126433-39-3 is a valid CAS Registry Number.
1126433-39-3Relevant academic research and scientific papers
Benzotriazole-assisted solid-phase assembly of Leu-Enkephalin, amyloid β segment 34-42, and other "difficult" peptide sequences
Katritzky, Alan R.,Haase, Danniebelle N.,Johnsons, Jodie V.,Chung, Alfred
body text, p. 2028 - 2032 (2009/08/07)
Microwave-assisted solid-phase syntheses of six "difficult" peptides, H-VVSVV-NH2 (3), H-VVVSVV-NH2(4), H-VIVIG-OH (5), H-TVTVTV-NH2 (6), H-VKDGYI-NH2 (7), and H-VKDVYI-NH2 (8), were achieved utilizing N-(Fmoc-α-aminoacyl) benzotriazoles. Extension to the syntheses of Leu-enkephalin (9) and amyloid-β (34-42) (10) demonstrates that this strategy comprises an efficient route to new and known "difficult" peptides.
