112652-46-7

Usage

Uses

Used in Pharmaceutical Industry:
Fragransin A2 is used as an antimicrobial agent for its potent antifungal and antibacterial activities. It serves as a promising candidate for the development of new antimicrobial drugs to combat resistant infections and emerging pathogens.
Used in Agricultural Industry:
Fragransin A2 is used as a biocontrol agent to protect plants against pathogenic fungi. Its natural origin and bioactivity make it a suitable alternative to conventional chemical fungicides, offering an eco-friendly and sustainable approach to managing plant diseases and promoting crop health.

Upstream product

• 915158-87-1 C₂₇H₃₀O₅ 
• 2426-87-1 3-methoxy-4-(phenylmethoxy)benzaldehyde 
• 1536264-02-4 C₃₆H₄₀O₁₁S₂ 
• 1536263-72-5 (7R,7′R,8S,8′S)-4,4′-dibenzyloxy-3,3′-dimethoxy-7,7′-epoxylignane-9,9′-diol 
• 1536263-75-8 (7S,7′S,8R,8′R)-4,4′-dibenzyloxy-3,3′-dimethoxy-7,7′-epoxylignane-9,9′-diol 
• 10569-12-7 (-)-Galbelgin 
• 1536263-89-4 (7R,7′S,8S,8′R)-4,4′-dibenzyloxy-3,3′-dimethoxy-7,7′-epoxylignane-9,9′-diol 
• 528-63-2 galgravin 
• 88497-87-4 manassantin A 
• 915158-62-2 (2R,3R,4R)-4-(4-allyloxy-3-methoxyphenyl)-4-(tert-butyldimethylsilanyloxy)-2,3-dimethylbutyraldehyde 
• 149777-72-0 4-Bromo-2-methoxy-1-<(tert-butyldimethylsilyl)oxy>benzene 
• 954114-83-1 (2R,3S)-3-(4-(benzyloxy)-3-methoxyphenyl)-3-((tert-butyldimethylsilyl)oxy)-2-methylpropan-1-ol 
• 954114-82-0 C₃₀H₄₃NO₆Si 
• 954114-81-9 C₂₄H₂₉NO₆ 

Downstream Products

• 91377-15-0 malabaricanol diacetate 
• 5701-82-6 1,4-bis(3,4-dimethoxyphenyl)-2,3-dimethylbutane 
• 3569-00-4 (+/-)-trans-4-(3,4-dimethoxyphenyl)-3,4-dihydro-6,7-dimethoxy-2,3-dimethylnaphthalene 
• 528-63-2 veraguensin 
• 528-63-2 galgravin 
• 10569-12-7 (-)-Galbelgin 
• 61949-24-4 (+)-galbelgin 
• 1204656-82-5 C₄₂H₄₈O₁₁ 
• 528-63-2 galbelgin 

Relevant academic research and scientific papers

Synthesis of all stereoisomers of 3,3′-dimethoxy-7,7′- epoxylignane-4,4′-diol and their plant growth inhibitory activity

All stereoisomers of 3,3′-dimethoxy-7,7′-epoxylignane-4, 4′-diol were synthesized to examine the effect of stereochemistry on their plant growth inhibitory activity using lettuce and Italian ryegrass. The effect of structural modifications such as dehydro

Synthesis of all stereoisomers of 3,3-Dimethoxy-7,7-epoxylignane-4,4-diol and their plant growth inhibitory activity

All stereoisomers of 3,3-dimethoxy-7,7-epoxylignane-4,4-diol were synthesized to examine the effect of stereochemistry on their plant growth inhibitory activity using lettuce and Italian ryegrass. The effect of structural modifications such as dehydroxyla

Glycosides from the bark of Machilus robusta

Six new glycosidic constituents (1-6), together with 10 known analogs, have been isolated from the bark of Machilus robusta. Structures of the new compounds, including the absolute configurations, were determined by spectroscopic and chemical methods as (

MANASSANTIN COMPOUNDS AND METHODS OF MAKING AND USING SAME

Provided are manassantin compounds and methods of using the compounds. Provided are methods of treating a disease, the method comprising administering a compound according to Formula I. Further provided are pharmaceutical compositions comprising compounds

Analysis of HIF-1 inhibition by manassantin A and analogues with modified tetrahydrofuran configurations

We have shown that manassantin A downregulated the HIF-1α expression and inhibited the secretion of VEGF. We have also demonstrated that the 2,3-cis-3,4-trans-4,5-cis-configuration of the tetrahydrofuran is critical to the HIF-1 inhibition of manassantin

Total synthesis and stereochemical confirmation of 2,5-diaryl-3,4- dimethyltetrahydrofuran lignans: (+)-Fragransin A2, (+)-galbelgin, (+)-talaumidin, (-)-saucernetin and (-)-verrucosin

A new ring closure to tetrasubstituted tetrahydrofurans from the intramolecular attack of an OMOM ether onto a benzylic mesylate proceeds through a quinonoid intermediate or by direct SN2 displacement. The synthesis of diastereomeric biological

Stereoselective synthesis of tetrahydrofuran lignans via BF 3·OEt2-promoted reductive deoxygenation/ epimerization of cyclic hemiketal: Synthesis of (-)-odoratisol C, (-)-futokadsurin A, (-)-veraguensin, (+)-fragransin A2, (+)-galbel

A versatile route to the synthesis of 2,5-diaryl-3,4- dimethyltetrahydrofuran lignans, (-)-odoratisol C. (1), (-)-futokadsurin A (2), (-)-veraguensln (3), (+)-fragransin A2 (4), (+)-galbelgin (5), and (+)-talaumidin (6), is described. Central t

O-demethylation of 7,7'-epoxylignans by Aspergillus niger

Biotransformation of the 7,7'-epoxylignans, (+)-veraguensin, (+)- galbelgin and galgravin by Aspergillus niger has been investigated. These lignans were converted to their corresponding 4,4'-O-demethyl derivatives, (+)-verrucosin, (+)-fragransin A2/

MANASSANTINS A/B AND SAUCERNEOL: NOVEL BIOLOGICALLY ACTIVE LIGNOIDS FROM SAURURUS CERNUUS

From the extract of Saururus cernuus two toxic principles, manassantins A and B and a related substance, saucerneol, were isolated.They have novel dineolignan or sesquineolignan type structures.Although toxic, manassantin A showed potential neuroleptic activity.