1126527-51-2Relevant academic research and scientific papers
Bu4NI-Catalyzed Cross-Coupling between Sulfonyl Hydrazides and Diazo Compounds to Construct β-Carbonyl Sulfones Using Molecular Oxygen
Wang, Yaxiong,Ma, Liang,Ma, Meihua,Zheng, Hao,Shao, Ying,Wan, Xiaobing
supporting information, p. 5082 - 5085 (2016/10/14)
A new cross-coupling reaction between sulfonyl hydrazides and diazo compounds has been established, leading to a variety of β-carbonyl sulfones in good yields. This methodology was distinguished by simple manipulation, easily available starting materials, and wide substrate scope. A plausible mechanism involving a radical process was proposed based upon the experimental observations and literature.
ISOQUINOLINES AS POTASSIUM ION CHANNEL INHIBITORS
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Page/Page column 68, (2014/09/29)
A compound of formula (I) (I) wherein A, R1, R1a, R3 and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
