112653-25-5Relevant academic research and scientific papers
Asymmetric α-Amidoalkylation. Syntheses of Enantiomerically Pure α-Substituted Piperidines with 1-Camphanoyl-1,2,3,4-tetrahydropyridine
Wanner, Klaus Th.,Kaertner, Annerose
, p. 1253 - 1267 (2007/10/02)
In a novel asymmetric synthesis the homochiral enamide 1 is coupled with the silyl enol ethers 5a-c in a diastereoselective fashion to afford the amidoalkylation products 6/7a-c.These are employed in the synthesis of enantiomerically pure, in α-position R
