1126635-72-0

Usage

Uses

Used in Pharmaceutical Research:
1-(2-chlorophenyl)-1H-1,2,3-triazole-4-yl-methanol is used as a building block for the synthesis of new drug candidates due to its ability to interact with biological systems through its triazole and chlorophenyl moieties.
Used in Medicinal Chemistry:
1-(2-chlorophenyl)-1H-1,2,3-triazole-4-yl-methanol is used as a starting material for the development of bioactive compounds, given its potential to be a valuable component in the creation of novel pharmaceuticals.
Used in Antifungal Applications:
1-(2-chlorophenyl)-1H-1,2,3-triazole-4-yl-methanol is used as a potential antifungal agent, possibly due to its ability to inhibit fungal growth or disrupt essential fungal processes.
Used in Antiviral Applications:
1-(2-chlorophenyl)-1H-1,2,3-triazole-4-yl-methanol is used as a potential antiviral agent, possibly for its ability to interfere with viral replication or inhibit viral entry into host cells.
Used in Anticancer Applications:
1-(2-chlorophenyl)-1H-1,2,3-triazole-4-yl-methanol is used as a potential anticancer agent, possibly due to its ability to target and disrupt cancer cell processes, leading to the inhibition of tumor growth and progression.
Used in Drug Delivery Systems:
1-(2-chlorophenyl)-1H-1,2,3-triazole-4-yl-methanol may be used in the development of drug delivery systems to enhance the bioavailability and therapeutic outcomes of other pharmaceutical compounds, potentially through its interaction with biological systems.

Upstream product

• 95-51-2 o-chloroaniline 
• 3296-07-9 1-azido-2-chlorobenzene 
• 107-19-7 propargyl alcohol 

Downstream Products

• 1325724-90-0 1-(2-chlorophenyl)-4,5-dihydro-1H-1,2,3-triazole-4-carbaldehyde 
• 1038261-38-9 1-(2-chlorophenyl)-1H-1,2,3-triazole-4-carboxylic acid 

Relevant academic research and scientific papers

Design, synthesis and effect of triazole derivatives against some toxic activities of Bothrops jararaca venom

According to the World Health Organization, snakebite envenoming is a neglected disease that affects around 5.4 million people worldwide each year. In Brazil, in 2019 there were 29,000 cases of accidents, with 104 deaths. The genus Bothrops was responsibl

Design, synthesis, and biological evaluation of 4-((6,7-dimethoxyquinoline-4-yl)oxy)aniline derivatives as FLT3 inhibitors for the treatment of acute myeloid leukemia

FMS-like tyrosine kinase 3 (FLT3) was an important therapeutic target in acute myeloid leukemia (AML). We synthesized two series of 4-((6,7-dimethoxyquinoline-4-yl)oxy)aniline derivatives possessing the semicarbazide moiety and 2,2,2-trifluoro-N,N′-dimeth

Synthesis and biological evaluation of ursolic acid derivatives bearing triazole moieties as potential anti-Toxoplasma gondii agents

Ursolic acid (UA), a plant-derived compound, has many properties beneficial to health. In the present study, we synthesised three series of novel UA derivatives and evaluated their anti-Toxoplasma gondii activity both in vitro and in vivo. Most derivative

Design and synthesis of novel dehydroepiandrosterone analogues as potent antiproliferative agents

The aim of the present study was to determine the cytotoxic effects of a series of novel dehydroepiandrosterone derivatives containing triazole at the C16 position on human cancer cells. The cancer cells used in the present study were A549, Hel

Synthesis and biological evaluation of novel triazole-biscoumarin conjugates as potential antitubercular and anti-oxidant agents

Abstract: The synthesis of a new series of triazole-biscoumarin conjugates by using a molecular hybridization approach is described. The newly synthesized compounds 6a–k were evaluated for their in vitro antitubercular activity against active and dormant

One-Pot Synthesis of 1-Monosubstituted 1,2,3-Triazoles from Propargyl Alcohol

A one-pot synthesis of 1-monosubstituted-1,2,3-triazoles from propargyl alcohol and various aryl azides was achieved. This simple method provides concise and efficient access to various 1-monosubstituted 1,2,3-triazole derivatives through a three-step one

Synthesis of 1,2,3-triazole hydrazide derivatives exhibiting anti-phytopathogenic activity

A series of new 1,2,3-triazole derivatives have been prepared and screened for their antifungal activity against phytopathogenic fungi using the mycelium growth inhibition method in?vitro. The results indicated that the 1,2,3-triazole hydrazide scaffold d

Design, synthesis, molecular-docking and antimycobacterial evaluation of some novel 1,2,3-triazolyl xanthenones

As part of an ongoing effort to develop new antitubercular and antimicrobial agents, a series of substituted xanthenone derivatives (7a-p) were synthesized. Xanthenone derivatives (7a-p) were prepared via a one-pot three-component thermal cyclization reac

Green synthesis and antibacterial evaluation of some new 1-aryl-3-(1-aryl-1H-[1,2,3]triazol-4-yl)-propenones

A new series of 1-aryl-3-(1-aryl-1H-[1,2,3]triazol-4-yl)propenones (6a–6j) was synthesized by condensation of substituted acetophenones (5a–5c) with substituted 1-aryl-1H-[1,2,3]triazole-4-carbaldehydes (4a–4d) in the presence of potassium hydroxide under