1126650-66-5 Usage
Uses
Used in Pharmaceutical Research:
1-Boc-3-fluoroazetidine-3-carboxylic acid is used as a key intermediate in the synthesis of fluorinated peptides and bioactive molecules. Its incorporation into these molecules can potentially enhance their biological activity and pharmacological properties, such as improved metabolic stability and binding affinity to target receptors.
Used in Organic Synthesis:
In the field of organic synthesis, 1-Boc-3-fluoroazetidine-3-carboxylic acid serves as a versatile building block for the creation of complex organic molecules. Its unique structure allows for various synthetic transformations, enabling the development of novel compounds with potential applications in various industries.
Used in Peptide Synthesis:
1-Boc-3-fluoroazetidine-3-carboxylic acid is used as a Boc-protected amino acid derivative in peptide synthesis. The Boc protection group is crucial for protecting the carboxylic acid group during the synthesis process, allowing for selective activation and coupling of the amino acid to other peptide fragments. This results in the formation of fluorinated peptides with potential therapeutic applications.
Overall, 1-Boc-3-fluoroazetidine-3-carboxylic acid is a valuable compound in various applications across the pharmaceutical and chemical industries, offering unique opportunities for the development of innovative drugs and synthetic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 1126650-66-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,2,6,6,5 and 0 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1126650-66:
(9*1)+(8*1)+(7*2)+(6*6)+(5*6)+(4*5)+(3*0)+(2*6)+(1*6)=135
135 % 10 = 5
So 1126650-66-5 is a valid CAS Registry Number.
1126650-66-5Relevant academic research and scientific papers
N-(Substituted sulfonyl)benzamide derivative and preparation method and pharmaceutical application thereof
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Paragraph 0593; 0595; 0600-0603, (2019/04/17)
The invention relates to an N-(substituted sulfonyl)benzamide derivative and preparation method and pharmaceutical application thereof, in particular to an N-(substituted sulfonyl)benzamide derivativeshown as general formula (I), preparation method thereof, medicinal salts of the derivative, and their application as therapeutics, especially as Nav1.7 inhibitors, wherein substituents in the general formula (I) shown in the description are defined the same as in the description.
Synthesis of l-Boc-3-fluoroazetidine-3-carboxylic acid
Van Hende, Eva,Verniest, Guido,Deroose, Frederik,Thuring, Jan-Willem,Macdonald, Gregor,De Kimpe, Norbert
experimental part, p. 2250 - 2253 (2009/08/07)
Synthetic strategies toward 3-fluoroazetidine-3-carboxylic acid, a new cyclic fluorinated β-amino acid with high potential as building block in medicinal chemistry, were evaluated. The successful pathway includes the bromoflu-orination of N-(diphenylmethy
