1126701-20-9

Basic information

• Product Name: (E)-2-(4-bromophenyl)-2-penten-1-ol
• Synonyms: (E)-2-(4-bromophenyl)-2-penten-1-ol
• CAS NO: 1126701-20-9
• Molecular Weight: 241.128
• Mol File: 1126701-20-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-2-(4-bromophenyl)-2-penten-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-(4-bromophenyl)-2-penten-1-ol(1126701-20-9)
• EPA Substance Registry System: (E)-2-(4-bromophenyl)-2-penten-1-ol(1126701-20-9)

Safety Data

• Hazardous Substances Data: 1126701-20-9(Hazardous Substances Data)

Upstream product

• 6261-22-9 pent-2-yn-1-ol 
• 5467-74-3 4-Bromophenylboronic acid 

Relevant articles and documents

Cobalt(II)-catalyzed regio- And stereoselective hydroarylation of alkynes with organoboronic acids

The series of cobalt (II)-catalyzed cross-coupling reactions of organoboronic acids with alkynes was investigated. The reaction provided a convenient method for the synthesis of highly substituted olefins by using less expensive cobalt complexes as catalysts under base-free conditioned. The scope of organoboronic acids 1 and alkynes 2 in the addition reaction under the standard reaction conditions was also analyzed. Based on the known metal-catalyzed couplings of organometallic reagents and alkynes, a possible reaction mechanism for the present hydroarylation reaction was proposed. These are the first cobalt-catalyzed addition reactions of organoboronic acids to alkynes. The unusual trans stereochemistry for the hydroarylation of substituted propargyl alcohol and amine was observed. The results showed that the organoboronic acid plays a dual role, acting both as a carbon nucleophile as well as proton source in the reaction.