1126779-13-2

Upstream product

• 1126779-15-4 tert-butyl 4-(3-chloro-4-cyanophenyl)-3,5-dimethyl-1H-pyrazole-1-carboxylate 
• 1126779-17-6 2-chloro-4-[3,5-dimethyl-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-4-yl]benzonitrile 

Downstream Products

• 1126773-62-3 2-chloro-4-{1-[(2,4-dimethyl-1,3-thiazol-5-yl)methyl]-3,5-dimethyl-1H-pyrazol-4-yl}benzonitrile 
• 1126773-68-9 2-chloro-4-[1-(2-furylmethyl)-3,5-dimethyl-1H-pyrazol-4-yl]benzonitrile 
• 1126776-55-3 4-{1-[(1,3-dimethyl-1H-pyrazol-5-yl)methyl]-3,5-dimethyl-1H-pyrazol-4-yl}benzonitrile 
• 1126771-11-6 2-chloro-4-[3,5-dimethyl-1-(pyridin-4-ylmethyl)-1H-pyrazol-4-yl]benzonitrile 

Relevant academic research and scientific papers

SUBSTITUTED PYRAZOLE DERIVATIVES

The present invention provides a novel pyrazole derivative and an androgen receptor antagonist containing the derivative. The present invention provides a compound represented by the formula (I′) wherein R1 is a hydrogen atom, a group via a carbon atom, a group via a nitrogen atom, a group via an oxygen atom, or a group via a sulfur atom; R2 is a phenyl group having cyano (the phenyl group may further have substituent(s) other than cyano); R3 is a hydrogen atom, a group via a carbon atom, a group via a nitrogen atom, a group via an oxygen atom, or a group via a sulfur atom; R4 is a cyclic group optionally having substituent(s); and X is methylene optionally having substituent(s), or CO, or a salt thereof.