1126779-37-0

Upstream product

• 552846-17-0 tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole-1-carboxylate 
• 154607-01-9 4-bromo-2-chlorobenzonitrile 

Downstream Products

• 1126771-27-4 4-{1-[(6-bromopyridin-3-yl)methyl]-3,5-dimethyl-1H-pyrazol-4-yl}-2-chlorobenzonitrile 
• 1126777-09-0 2-chloro-4-[1-(4-cyanobenzyl)-1H-pyrazol-4-yl]benzonitrile 

Relevant academic research and scientific papers

SUBSTITUTED PYRAZOLE DERIVATIVES

The present invention provides a novel pyrazole derivative and an androgen receptor antagonist containing the derivative. The present invention provides a compound represented by the formula (I′) wherein R1 is a hydrogen atom, a group via a carbon atom, a group via a nitrogen atom, a group via an oxygen atom, or a group via a sulfur atom; R2 is a phenyl group having cyano (the phenyl group may further have substituent(s) other than cyano); R3 is a hydrogen atom, a group via a carbon atom, a group via a nitrogen atom, a group via an oxygen atom, or a group via a sulfur atom; R4 is a cyclic group optionally having substituent(s); and X is methylene optionally having substituent(s), or CO, or a salt thereof.