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6-Hydroxy TriMethopriM is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

112678-48-5

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112678-48-5 Usage

Chemical Properties

White Powder

Uses

Trimethoprim (T795615) derivative. Antibacterial properties.

Check Digit Verification of cas no

The CAS Registry Mumber 112678-48-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,6,7 and 8 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 112678-48:
(8*1)+(7*1)+(6*2)+(5*6)+(4*7)+(3*8)+(2*4)+(1*8)=125
125 % 10 = 5
So 112678-48-5 is a valid CAS Registry Number.

112678-48-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,6-Diamino-5-(3,4,5-trimethoxybenzyl)-4(5H)-pyrimidinone

1.2 Other means of identification

Product number -
Other names 4-Hydroxy Trimethoprim

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:112678-48-5 SDS

112678-48-5Upstream product

112678-48-5Downstream Products

112678-48-5Relevant academic research and scientific papers

2,4-Diamino-5-benzylpyrimidines and analogues as antibacterial agents. II. C-alkylation of pyrimidines with Mannich bases and application to the synthesis of trimethoprim and analogues

Roth,Strelitz,Rauckmann

, p. 379 - 384 (2007/10/02)

A new route to 5-(p-hydroxybenzyl)pyrimidines has been developed which utilizes phenolic Mannich bases plus pyrimidines containing at least two activating groups. The products can be alkylated on the phenolic oxygen or on the pyrimidine N-1 atom, depending on conditions. This method has been used to prepare trimethoprim, a broad-spectrum antibacterial agent, starting from 2,4-diaminopyrimidine and 2,6-dimethoxyphenol.

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