1126799-30-1Relevant academic research and scientific papers
Fac-[Re(CO)3L] complexes containing tridentate monoanionic ligands (L-) having a terminal amido and two amine ligating groups
Christoforou, Anna Maria,Marzilli, Patricia A.,Fronczek, Frank R.,Marzilli, Luigi G.
, p. 115 - 121 (2008)
Treatment of fac-[Re(CO)3(H2O)3] + with two unsymmetrical tridentate NNN donor ligands (LH) based on a diethylenetriamine (dien) moiety with a 2,4,6-trimethylbenzoyl (tmbCO) group linked to a terminal nitrogen of dien through an amide produced the neutral complexes [Re(CO)3(tmbCO-N,N-Me2dien)] and [Re(CO) 3(tmbCO-dien)]. The [Re(CO)3(tmbCO-N,N-Me 2dien)] complex crystallized in the space group P21/c, a = 19.5793 (15), b = 7.4239 (5), c = 14.8071 (10) A, β = 104.425(5)°, V = 2084.4(3) A3, and the [Re(CO) 3(tmbCO-dien)] complex crystallized in the space group C2/c, a = 36.861 (7), b = 7.3990 (10), c = 14.933 (3) A, β = 102.145 (8)°, V = 3981.6(12) A3. X-ray crystallographic and NMR analyses confirm that in both the solid and solution states the ligands are bound to the fac-Re(CO)3 core in a tridentate fashion with the amide group being deprotonated. An important property in radiopharmaceuticals is shape, which in turn depends on ring pucker. For [Re(CO)3(tmbCO-N,N-Me 2dien)], the two chelate rings have different pucker chirality, as is commonly found for a broad range of metal complexes. However, for fac-[Re(CO)3(tmbCO-dien)], the two chelate rings have the same pucker chirality, a finding attributable to two strong intermolecular hydrogen bonds from the NH2 to two waters of crystallization. Impeded by methyl group clashes with chelate ring hydrogens, the tmb ring rotation about the C(amido)-C(tmb) bond is slow on the NMR time scale. fac -[Re(CO) 3 L] Complexes Containing Tridentate Monoanionic Ligands (L - ) Having a Terminal Amido and Two Amine Ligating Groups Anna Maria Chirstoforou, Patricia A. Marzilli, Frank R. Fronczek, and Luigi G. Marzilli X-ray crystallographic and NMR analyses of fac-Re(CO)3 complexes containing diethylenetriamine-based, NNN tridentate ligands with a terminal deprotonated amido donor group allow comparison to previously reported analogues with a terminal deprotonated sulfonamido donor group.
