1126908-81-3

Basic information

• Product Name: 1-[dichloro-(3-methoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxyisoquinoline
• Synonyms: 1-[dichloro-(3-methoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxyisoquinoline
• CAS NO: 1126908-81-3
• Molecular Weight: 380.271
• Mol File: 1126908-81-3.mol

Chemical Properties

• CAS DataBase Reference: 1-[dichloro-(3-methoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxyisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[dichloro-(3-methoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxyisoquinoline(1126908-81-3)
• EPA Substance Registry System: 1-[dichloro-(3-methoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxyisoquinoline(1126908-81-3)

Safety Data

• Hazardous Substances Data: 1126908-81-3(Hazardous Substances Data)

Upstream product

• 608141-10-2 6,7-dimethoxy-1-(3'-methoxybenzyl)-1,2,3,4-tetrahydroisoquinoline 

Downstream Products

• 1126908-87-9 1-[methoxy-(3-methoxyphenyl)methyl]-6,7-dimethoxyisoquinoline 
• 1126908-90-4 1-[dimethoxy-(3-methoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxyisoquinoline 

Relevant articles and documents

New synthesis of 1-[(3,4-dimethoxyphenyl)methoxymethyl]-6,7-dimethoxyisoquinoline (setigerine), a naturally occurring alkaloid, and some derivatives of papaverine

A novel and improved synthetic route for the preparation of the new alkaloid setigerine, isolated from Papaver setigerum DC, and some new 3,4-dihydropapaverine and papaverine derivatives is reported. This method is based on the side chain chlorination of 1-benzyl-3,4-dihydroisoquinolines using N-chlorosuccinimide (NCS) and subsequent reaction with sodium methoxide in methanol to give the corresponding isoquinolines.