112697-72-0

Upstream product

• 7521-41-7 2-Aminonicotinaldehyde 
• 101-92-8 4'-Chloroacetoacetanilide 

Downstream Products

• 118965-66-5 3-[1-(4-Chloro-phenyl)-1H-tetrazol-5-yl]-2-methyl-[1,8]naphthyridine 

Relevant academic research and scientific papers

Indium(Iii) Chloride as an efficient catalyst for friedlander synthesis 1,8-Naphthyridines under solventfree conditions

InCl3 catalyzed Friedlander condensation of 2-aminonicotinaldehyde 1 with carbonyl compounds containing methylene group 2 has been achieved in solvent-free grinding conditions to give 1,8-naphthyridines 3 in high yields. The method is simple an

Cecl3.7H2O catalyzed Friedlander synthesis of 1,8-naphthyridines under solvent-free grinding conditions

CeCl3.7H2O catalyses the Friedlander condensation of 2-aminonicotinaldehyde 1 with varius carbonyl compounds containing α-methylene group 2 in solvent-free grinding conditions to afford the corresponding 1,8-naphthyridines 3. The rea

ZrOClinf2/inf.8Hinf2/infO catalyzed solvent-free Friedlander synthesis of 1,8-naphthyridines

ZrOClinf2/inf.8Hinf2/infO catalyzed Friedlander condensation of 2-Aminonicotinaldehyde 1 with carbonyl compounds containing-methylene group 2 has been achieved in solvent-free grinding conditions to give 1,8-naphthyridines 3. The yields are very good and

Green approach for the efficient synthesis of 1,8-naphthyridines promoted by citric acid

Citric acid catalyzed Friedlander condensation of 2-aminonicotinaldehyde 1 with various carbonyl compounds containing α-methylene group 2 has been achieved under neat conditions at 100° to give the corresponding 1,8-naphthyridines 3. The products are obta

An efficient Friedlander condensation using Zr(OH)2CO 3.ZrO2 as catalyst in the solid state

A simple and efficient Friedlander condensation of 2-aminonicotinaldehyde 1 with various carbonyl compounds containing α- methylene group 2 under solid state conditions to prepare 1,8- naphthyridines 3 in very good yields using Zr(OH)2CO3

Potassium triiodide catalyzed Friedlander synthesis of 1,8-naphthyridines in aqueous media

Potassium triiodide catalyses the Friedlander condensation of 2-aminonicotinaldehyde 1 with carbonyl compounds containing α-methylene group 2 in aqueous media to afford 1,-naphthyridines 3 in high yields.

Al2O3 catalyzed Friedlander synthesis of 1, 8-naphthyridines in the solid state

Al2O3 catalyzes efficiently the Freidlander condensation of 2-aminonicotinaldehyde 1 with various carbonyl compounds containing α-methylene group 2 in the solid state to afford the corresponding 1.8-naphthyridines 3. The reaction pro

Lithium chloride as an efficient catalyst for Friedlander synthesis of 1,8-naphthyridines via the use of microwave irradiation and pestle/mortar

An efficient, practical and eco-friendly method of preparation of 1,8-naphthyridines 3 has been reported by Friedlander condensation between 2-aminonicotinaldehyde 1 and active methylene compounds 2 in the presence of lithium chloride in combination with

Montmorillonite K 10 clay catalyzed Friedlander synthesis of 1,8-naphthyridines in dry media under microwave irradiation

Montmorillonite K 10 clay catalyzed Friedlander condensation of 2-aminonicotinaldehyde 1 with carbonyl compounds containing α-methylene group 2 has been achieved in solvent-free condition under microwave irradiation to give 1,8-naphthyridine derivatives 3

PTSA-catalyzed Friedlander condensation in the solid state

Friedlander condensation is assisted by p-toluenesulphonic acid (PTSA) wherein various active methylene compounds 2 react readily with 2-aminonicotinaldehyde 1 in the solid state to produce corresponding 1, 8-naphthyridines 3. The reaction proceeds effici