112700-47-7Relevant academic research and scientific papers
Facile synthesis of unsaturated pyroglutaminol derivatives
Oba, Makoto,Ito, Chihiro,Hayashi, Takahiro,Nishiyama, Kozaburo
scheme or table, p. 5053 - 5055 (2009/12/05)
A novel approach to the synthesis of unsaturated pyroglutaminol derivatives was developed. Condensation of a protected serine derivative with Meldrum's acid followed by decarboxylative cyclization afforded a tetramic acid, which was then converted to a hy
Stereospecific Synthesis of N-Protected Statine and Its Analogues via Chiral Tetramic Acid
Jouin, Patrick,Castro, Bertrand,Nisato, Dino
, p. 1177 - 1182 (2007/10/02)
The condensation of a chiral N-protected amino acid with Meldrum's acid in the presence of isopropenyl chloroformate (IPCF) and of 4-N,N-dimethylaminopyridine (DMAP) has been examined.The cyclisation of the reaction product, by heating in an organic solve
