112701-05-0Relevant academic research and scientific papers
REACTIONS OF METALLATED 1,3-DITHIANES WITH CARBOXYLIC ACID DERIVATIVES
Page, Philip C. Bulman,van Niel, Monique B.,Westwood, Donald
, p. 269 - 276 (2007/10/02)
2-Lithio-1,3-dithiane and 2-lithio-2-trimethylsilyl-1,3-dithiane react with nitriles to afford primary aminoketene dithioacetals in good yields; these compounds exhibit marked ambident nucleophilicity.Use of other carboxylic acid derivatives as electrophi
Chemistry of Aminoketene Dithioacetals: Preparation of Protected α-Amino Aldehydes and Ketones and Formation of Nitrogen Heterocycles
Page, Philip C. Bulman,Niel, Monique B. van,Westwood, Donald
, p. 775 - 776 (2007/10/02)
The ambient anion (2) derived from primary aminoketene dithioacetal (1, R = Ph) reacts with alkyl halides at the carbon atom to give remarkably stable imines which may be reduced to give protected α-amino ketones using borane in quantitative yield, and un
