112706-72-6 Usage
General Description
1-Methyl-6-fluorothymine is a chemical compound that is a modified form of thymine, one of the four nucleobases in DNA. It is a synthetic nucleoside analog that contains a fluorine atom at the 6 position of the thymine ring and a methyl group at the 1 position. This chemical modification imparts unique properties to 1-methyl-6-fluorothymine, making it a potential candidate for use in the development of antiviral and anticancer drugs. It has been studied for its potential as a building block for nucleoside analogs that could exhibit improved efficacy and reduced toxicity compared to existing treatments. The chemical structure and properties of 1-methyl-6-fluorothymine make it a promising target for further research and development in the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 112706-72-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,7,0 and 6 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 112706-72:
(8*1)+(7*1)+(6*2)+(5*7)+(4*0)+(3*6)+(2*7)+(1*2)=96
96 % 10 = 6
So 112706-72-6 is a valid CAS Registry Number.
InChI:InChI=1/C6H7FN2O2/c1-3-4(7)9(2)6(11)8-5(3)10/h1-2H3,(H,8,10,11)
112706-72-6Relevant articles and documents
Studies of vibrational spectra of 6-fluorothymine and its methyl derivatives
Stepanian, S. G.,Smorygo, N. A.,Sheina, G. G.,Radchenko, E. D.,Yakovleva, V. D.,et al.
, p. 355 - 361 (1990)
The solid and the argon-matrix isolated samples of 6-fluorothymine, 1-methyl-6-fluorothymine, 1,3-dimethyl-6-fluorothymine and 3-methylfluorothymine are studied at low temperatures by i.r. spectroscopy.The spectra obtained are interpreted using the calculation of planar normal vibration frequencies.The electronegative fluorine atom in the 6-position is shown to have a strong influence on the normal vibration frequency changes of crystalline and isolated thymine.N-H...F hydrogen bonds are evidenced to exist in crystalline samples.