112711-40-7

Upstream product

• 21204-67-1 methyl (triphenylphosphoranylidene)acetate 
• 3956-31-8 benzyl (2S,5R,6R)-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 

Downstream Products

• 85339-60-2 benzyl 6β-penicillanate 
• 85339-59-9 benzyl (2S,5R,6R)-6--7-methoxycarbonyl-(Z)-methylene-3,3-dimethyl-4-thia-1-azabicyclo<3.2.0>heptane-2-carboxylate 
• 112790-55-3 benzyl (2S,5R,6R)-6--7-methoxycarbonyl-(E)-methylene-3,3-dimethyl-4-thia-1-azabicyclo<3.2.0>heptane-2-carboxylate 

Relevant academic research and scientific papers

Wittig Reactions with β-Lactam Carbonyl Functions. The Effect of C-7 Substitution on the Chemistry of Penicillins and Clavulanic Acid Derivatives.

The Wittig reaction of phosphoranes and phosphonates with the carbonyl function of mono- and bicyclic β-lactams has been studied and the inluence of phosphorane and β-lactam reactivities on the outcome of the reaction noted.The utility and general chemist

1-Aza-[3.2.0]-bicycloheptane-2-carboxylic acid, ester or salt thereof

A 1-aza[3.2.0]bicycloheptan-2-carboxylic acid or salt or ester thereof having a substituent at position 7 of the formula: wherein R1 and R2 are independently hydrogen, halogen or an organic group.