112741-51-2

Usage

Uses

Used in Pharmaceutical Industry:
(3S,5S,6R)-tert-Butyl 3-bromo-2-oxo-5,6-diphenylmorpholine-4-carboxylate is used as a potential pharmaceutical candidate for [specific application reason] due to its complex structure and functional groups that are often present in drug molecules.
Used in Chemical Reactions:
In the chemical industry, (3S,5S,6R)-tert-Butyl 3-bromo-2-oxo-5,6-diphenylmorpholine-4-carboxylate is used as a reactant or intermediate in the synthesis of other compounds for [specific application reason], taking advantage of its unique structural features and reactivity.
(Note: The specific application reasons for the pharmaceutical and chemical industries would need to be determined through further research and analysis, as the provided materials do not specify these details.)

Upstream product

• 100678-82-8 2-((1S,2R)-2-hydroxy-1,2-diphenylethylamino)acetic acid ethyl ester 
• 112741-70-5 (1'S,2'R)-ethyl N-(tert-butyloxycarbonyl)-N-(1',2'-diphenyl-2'-hydroxyethyl)glycinate 
• 23190-16-1 (1R,2S)-2-Amino-1,2-diphenylethanol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 112741-49-8 tert-butyl (2R,3S)-6-oxo-2,3-diphenylmorpholine-4-carboxylate 

Downstream Products

• 112741-64-7 (3S,5S,6R)-3-(R)-Cyclopent-2-enyl-2-oxo-5,6-diphenyl-morpholine-4-carboxylic acid tert-butyl ester 
• 112741-63-6 (3S,5S,6R)-4-(tert-butyloxycarbonyl)-3-(2'-cyclopentenyl)-5,6-diphenyl-2,3,5,6-tetrahydro-4H-1,4-oxazin-2-one 
• 112741-54-5 (3S,5S,6R)-4-(tert-butyloxycarbonyl)-5,6-diphenyl-3-(1'-prop-2'-enyl)-2,3,5,6-tetrahydro-4H-1,4-oxazin-2-one 
• 136328-42-2 (3S,5S,6R)-4-(tert-butoxycarbonyl)-3-(dimethoxyphosphoryl)-5,6-diphenyl-2,3,5,6-tetrahydro-4H-1,4-oxazin-2-one 
• 90600-20-7 (2S)-2-[(tert-butoxycarbonyl)amino]pent-4-enoic acid 
• 136328-51-3 (E)-(5S,6R)-4-(tert-butoxycarbonyl)-5,6-diphenyl-3-ethylidene-2,3,5,6-tetrahydro-4H-1,4-oxazin-2-one 
• 136328-52-4 (E)-(5S,6R)-4-(tert-butoxycarbonyl)-5,6-diphenyl-3-propylidene-2,3,5,6-tetrahydro-4H-1,4-oxazin-2-one 
• 136328-54-6 (E)-(5S,6R)-4-(tert-butoxycarbonyl)-3-isobutylidene-5,6-diphenyl-2,3,5,6-tetrahydro-4H-1,4-oxazin-2-one 
• 136328-53-5 (E)-(5S,6R)-4-(tert-butoxycarbonyl)-3-butylidene-5,6-diphenyl-2,3,5,6-tetrahydro-4H-1,4-oxazin-2-one 
• 136328-55-7 (E)-(5S,6R)-3-benzylidene-4-(tert-butoxycarbonyl)-5,6-diphenyl-2,3,5,6-tetrahydro-4H-1,4-oxazin-2-one 
• 136328-56-8 (E)-(5S,6R)-5,6-diphenyl-3-(4'-nitrobenzylidene)-4-(tert-butoxycarbonyl)-2,3,5,6-tetrahydro-4H-1,4-oxazin-2-one 

Relevant academic research and scientific papers

Asymmetric syntheses of 1-aminocyclopropane-1-carboxylic acid derivatives

Optically active D-erythro-4-(tert-butoxycarbonyl)-3-(dimethoxyphosphoryl)-5,6-diphenyl-2,3,5,6- tetrahydro-4H-1,4-oxazin-2-one (13) can be efficiently condensed with various aldehydes via the Emmons-Horner-Wadsworth procedure to provide α,β-dehydrolacton

Practical Asymmetric Syntheses of α-Amino Acids through Carbon-Carbon Bond Constructions on Electrophilic Glycine Templates

The optically active D- and L-erythro-4-(benzyloxycarbonyl)-5,6-diphenyl-2,3,5,6-tetrahydro-4H-1,4-oxazin-2-ones (3) and D- and L-erythro-4-(tert-butoxycarbonyl)-5,6-diphenyl-2,3,5,6-tetrahydro-4H-1,4-oxazin-2-ones (3) can be efficiently brominated to serve as electrophilic glycine templates for the asymmetric synthesis of amino acids.It was found that coupling to these templates can proceed with either net retention or net inversion of stereochemistry.The final deblocking to the amino acids is accomplished with either dissolving-metal reduction or catalytic hydrogenolysis.The syntheses of β-ethyl aspartic acid, norvaline, allylglycine, alanine, norleucine, homophenylalanine, p-methoxyhomophenylalanine, cyclopentylglycine, and cyclopentenylglycine and a formal synthesis of clavalanine are described.In addition, the direct asymmetric syntheses of N-t-BOC-allylglycine and N-t-BOC-cyclopentenylglycine are described.