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Usage

Uses

Used in Pharmaceutical Industry:
1-(2-bromo-5-hydroxyphenyl)ethanone serves as a crucial intermediate in the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its unique chemical structure allows for versatile reactions and modifications, facilitating the creation of diverse medicinal compounds.
Used in Fragrance Industry:
In the fragrance industry, 1-(2-bromo-5-hydroxyphenyl)ethanone is used as a key intermediate for the production of various scent compounds. Its aromatic properties and ability to react with other molecules make it a valuable component in creating unique and complex fragrances.
Used in Organic Compounds Synthesis:
1-(2-bromo-5-hydroxyphenyl)ethanone is utilized as an intermediate in the synthesis of a wide range of organic compounds, including dyes, polymers, and other specialty chemicals. Its reactivity and structural features enable the production of various organic materials with specific properties and applications.
Used in Biological Research:
Due to its potential antioxidant and anti-inflammatory properties, 1-(2-bromo-5-hydroxyphenyl)ethanone is studied in biological research for its possible applications in medicine and healthcare. Its ability to modulate biological processes and exhibit therapeutic effects makes it a promising candidate for further investigation and development in the field of bioactive compounds.

Upstream product

• 121-71-1 3-Hydroxyacetophenone 

Downstream Products

• 1586824-39-6 C₁₆H₁₅BrN₂O₃ 

Relevant academic research and scientific papers

Aromatic bromination of aldehydes and ketones using 1,3-di-n- butylimidazolium

An environmentally benign and efficient process for the preparation of monobromo derivatives of aryl aldehydes and ketones was developed by simple and practical reactions of aryl aldehydes or ketones with 1,3-di-n-butylimidazolium tribromide ([BBIm]Br3), as a brominating reagent under solvent-free conditions in very high yields. The process has several advantages: high conversions, short reaction time, mild reaction conditions, simple workup with good to quantitative yields and re-usable ionic liquid.

Facile p-toluenesulfonic acid-promoted para-selective monobromination and chlorination of phenol and analogues

para-Regioselective bromination of phenol and analogues, promoted by p-toluenesulfonic acid, is achieved in high to excellent yields at room temperature with N-bromosuccinimide. Chlorination with N-chlorosuccinimide and catalysed by p-toluenesulfonic acid also gives para-chlorinated phenol analogues in good yields at room temperature. para-Bromination of phenol, promoted by p-toluenesulfonic acid, is achieved in excellent yields at room temperature with N-bromosuccinimide. p-Toluenesulfonic acid is also effective as a promoter of para-chlorination with N-chlorosuccinimide.

An efficient, rapid, and regioselective bromination of anilines and phenols with 1-butyl-3-methylpyridinium tribromide as a new reagent/solvent under mild conditions

1-Butyl-3-methylpyridinium tribromide, [BMPy]Br3 proves to be a highly efficient, regioselective reagent/solvent for nuclear bromination of various anilines and phenols. The synthesis and characterization of the room temperature ionic liquid [BMPy]Br3 (2) is described. The bromination was carried out in the absence of organic solvents and in most cases the only extraction solvent needed was water. The spent 1-butyl-3-methylpyridinium bromide (1) was easily recycled.