112754-23-1Relevant academic research and scientific papers
Study of reactivity of 3-fluoro 2-oxo acid derivatives synthesis of fluorinated alcohols, schiff bases, oximes, hydrazones, and quinoxalines derivatives
Remli, M.,Ayi, A. I.,Condom, R.,Guedj, R.
, p. 864 - 867 (2007/10/02)
Ring opening of 2,3-epoxynitriles with hydrogen fluoride in pyridine gives 3-fluoro 2-hydroxynitriles in good yields.Oxidation of the fluorocyanhydrins by the Jones' reagent provides a good method for the preparation of fluoro pyruvic acid derivatives.These compounds have been found to be versaile intermediates leading to a variety of new classes of monofluorinated products e.g.,fluoroalcohols, fluoro Schiff's bases, oximes, hydrazones and quinoxalines derivatives.
