112797-76-9Relevant academic research and scientific papers
AMINOALCOHOL DERIVATIVES
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Page/Page column 45, (2010/02/14)
The present invention relates to a compound formula[I]: wherein X is bond or -O-, R1 is formula[A] or formula [B] in which R5, R6 and R7 are each as defined in the description, R2 is hydrogen or lower alkyl, R3 is hydrogen or an amino protective group , R4 is formula[C], [D] or [E] in which R8, R9, R10, R11, R12, R13 and R16are each as defined in the description, and R14 and R15 are each independently hydrogen or lower alkyl, or a prodrug thereof or a salt thereof. The compound [I] of the present invention and pharmaceutically acceptable salts thereof are useful for the prophylactic and/or the therapeutic treatment of overactive bladder, micturiation disorder and the like.
New route to styrylchromones via [1-(2-hydroxybenzoyl)alkylidene]triphenylphosphoranes
Zammattio,Brion,Le Baut,Ducrey
, p. 375 - 376 (2007/10/02)
Several [1-(2-hydroxybenzoyl)alkylidene]triphenylphosphoranes have been obtained in good yields through acylation of the corresponding alkylidenetriphenylphosphoranes, prepared in situ, by the easily available methyl 2-hydroxybenzoates. These ylides prove
