1128045-87-3

Basic information

• Product Name: 3-chloro-N-((3,5,6-trimethylpyrazin-2-yl)methyl)benzamide
• Synonyms: 3-chloro-N-((3,5,6-trimethylpyrazin-2-yl)methyl)benzamide
• CAS NO: 1128045-87-3
• Molecular Weight: 289.765
• Mol File: 1128045-87-3.mol

Chemical Properties

• CAS DataBase Reference: 3-chloro-N-((3,5,6-trimethylpyrazin-2-yl)methyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloro-N-((3,5,6-trimethylpyrazin-2-yl)methyl)benzamide(1128045-87-3)
• EPA Substance Registry System: 3-chloro-N-((3,5,6-trimethylpyrazin-2-yl)methyl)benzamide(1128045-87-3)

Safety Data

• Hazardous Substances Data: 1128045-87-3(Hazardous Substances Data)

Upstream product

• 75907-74-3 2-Pyrazinemethanol,3,5,6-trimethyl 
• 1128046-47-8 N-((3,5,6-trimethylpyrazin-2-yl)methyl)isoindole-1,3-dione 
• 1124-11-4 Tetramethylpyrazine 
• 866751-49-7 1‐(3,5,6‐trimethylpyrazin‐2‐yl)methanamine 
• 618-46-2 m-Chlorobenzoyl chloride 

Relevant articles and documents

Ligustrazine derivatives. Part 8: Design, synthesis, and preliminary biological evaluation of novel ligustrazinyl amides as cardiovascular agents

A series of novel Ligustrazinyl amides was designed, synthesized and evaluated for their protective effect onthe injured vascular endothelial cells. The preliminary results demonstrated that some compounds possessed more potentactivities than that of Ligustrazine in stimulating replication of the injured human umbilical vascular endothelial cells(HUVECs) that is damaged by hydrogen peroxide. Among the active compounds, compounds 8i, 8t and 8u exhibited thehighest potency with low EC50 values of 0.037, 0.070 and 0.055 mM, respectively. Structure-activity relationships werebriefly discussed.