1128054-21-6Relevant articles and documents
Gold or no gold: One-pot synthesis of tetrahydrobenz[b]azepin-4-ones from tertiary n-(but-3-ynyl)anilines
Cui, Li,Zhang, Guozhu,Peng, Yu,Zhang, Liming
supporting information; experimental part, p. 1225 - 1228 (2009/08/07)
Depending on the tertiary aniline substrates, an efficient, one-pot synthesis of tetrahydrobenz[b]azepin-4-ones needs either gold catalysts or no catalyst at all. In the reaction, the aniline nitrogen plays a unique role in relaying "O" from m-CPBA to a tethered C-C triple bond, which is inert to the oxidant under the mild reaction conditions.
