112815-98-2Relevant academic research and scientific papers
JNK INHIBITOR
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Page/Page column 101, (2010/02/07)
The present invention relates to a c-Jun N-terminal kinase inhibitor containing an azole compound (I) substituted by a nitrogen-containing aromatic group having substituent(s)(except a compound represented by the formula: ) or a salt thereof or a prodrug thereof.
SYNTHESES OF 1-PHENYL-2-(4-PYRIMIDINYL)ETHANONE AND RELATED ETHANONES.
Sund,Strickland
, p. 216 - 217 (2007/10/02)
Eleven 1-phenyl-2-(4-pyrimidinyl)ethanones were synthesized by the condensation of 4-methylpyrimidine and the requisite methyl benzoate ester with sodium hydride as the condensing agent. Substituents in the 3-and 4-position of the phenyl ring were chloro, dimethylamino, methoxy, methyl, and trifluoromethyl.
