112863-58-8Relevant academic research and scientific papers
Organocatalyst-mediated enantioselective intramolecular Michael addition of aldehydes to vinyl sulfones
Bournaud, Chloee,Marchal, Estelle,Quintard, Adrien,Sulzer-Mosse, Sarah,Alexakis, Alexandre
experimental part, p. 1666 - 1673 (2010/10/04)
Chiral amines with a hydrogen bond donor promote the intramolecular conjugate addition of aldehydes to vinyl sulfones. Chiral cyclic sulfone-aldehydes are obtained in good yields with an ee of up to 82%.
Intramolecular Diels-Alder additions to 2-benzopyran-3-ones; anti-selectivity induced by the phenylsulfonyl group
Bush, Edward J.,Jones, David W.,Ryder, Tracie C. L. M.
, p. 1929 - 1938 (2007/10/03)
Intramolecular Diels-Alder additions of the 2-benzopyran-3-ones 2d, 2e and 2f with an E-SO2Ph substituent on the dienophile (X = SO2Ph in 2) show greatly enhanced exo-addition of the tether than is shown in the absence of the E-SO2Ph group (X = H in 2). For 2e and 2f, exo-chain addition becomes preferred, and for 2d, endo-chain addition much less preferred, than in related cases with X = H. An E-CO2Me group on the dienophile is also effective in enhancing exo-chain addition, but less effective than an E-SO2Ph group. The adducts 4e and 4f undergo reductive elimination (5% Na-Hg) to give the diterpene related products 32 and 33 respectively.
A Free Radical Addition-Fragmentation Reaction for the Preparation of Vinyl Sulfones and Phosphine Oxides
Keck, Gary E.,Byers, Jeffrey H.,Tafesh, Ahmed M.
, p. 1127 - 1128 (2007/10/02)
A free radical chain process is reported which gives vinyl sulfones or phosphine oxides in good to moderate yields under nonreducing conditions; the reaction involves irradiation of appropriate precursors to carbon-centered radicals with β-tri-n-butylstan
