112881-47-7Relevant articles and documents
A versatile domino synthesis affording novel S- and U-shaped terpyridines. Synthesis, properties and crystal structure
Keuper, Ralf,Risch, Nikolaus,Floerke, Ulrich,Haupt, Hans-Juergen
, p. 705 - 715 (2007/10/03)
The development of a simple and general method for the preparation of multifunctional terpyridines is described. The treatment of the ketones 1a-g with ternary iminium salts results in the formation of the isomeric terpyridines 6 and 8 (according to a domino reaction). A possible reaction mechanism is discussed. In some cases the isolation of the postulated dihydropyridine intermediates was successful. The isolation of the 1,4-dihydropyridines 5e, 5j, and 5r (donor-substituted) is surprising, because most of the stable dihydropyridines are acceptor-substituted. In several cases the yields of such domino reactions are very high (>80%). Whether S-or U-shaped terpyridines are formed is immediately recognized by NMR spectroscopy. Some special cases (8c, 8e, 6h) were investigated by means of single-crystal X-ray analysis. VCH Verlagsgesellschaft mbH, 1996.
POLYAZA CAVITY SHAPED MOLECULES 13. A VERSATILE NEW TERPYRIDINE SYNTHESIS
Hegde, Vidyadhar,Jahng, Yurngdong,Thummel, Randolph P.
, p. 4023 - 4026 (2007/10/02)
The reaction of morpholine enamines derived from α-pyridyl ketones with aromatic aldehydes leads to the formation of a 1,5-diketone intermediate which in turn provides a 4'-substituted derivative of 2,2',6',2''-terpyridine.
