112897-80-0Relevant articles and documents
Steroids, XXXVII. - Neighbouring Group Participation, VIII. - Neighbouring Group Participation in the 16-Hydroxymethyl-3-methoxyestra-1,3,5(10)-trien-17β-ol Series
Schneider, Gyula,Vass, Andras,Vincze, Iren,Sohar, Pal
, p. 267 - 274 (2007/10/02)
Reduction of the acetoxymethylene ketone 1b yielded a mixture of two epimeric diols 3a and 4a, which were converted into the p-toluenesulfonates 3d and 4d.Solvolysis of 3d in dry acetic acid afforded 5b after inversion at C-17.As an explanation for the fo