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C-(4-PHENYL-MORPHOLIN-2-YL)-METHYLAMINE, an organic amine derivative with the molecular formula C14H19N2O, features a central morpholine ring to which a phenyl group is attached at the 4-position and a methylamine group is connected to the central carbon atom. C-(4-PHENYL-MORPHOLIN-2-YL)-METHYLAMINE is recognized for its structural and reactivity attributes, positioning it as a valuable component in the synthesis of bioactive compounds and drug molecules.

112913-99-2

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112913-99-2 Usage

Uses

Used in Pharmaceutical Industry:
C-(4-PHENYL-MORPHOLIN-2-YL)-METHYLAMINE is utilized as a building block for the synthesis of various bioactive compounds and drug molecules. Its unique chemical structure and reactivity contribute to the development of new drug candidates and potential therapeutic agents for a range of medical conditions.
Used in Chemical Research:
Beyond its pharmaceutical applications, C-(4-PHENYL-MORPHOLIN-2-YL)-METHYLAMINE also serves as a valuable component in chemical research, where it can be employed to explore new chemical reactions and mechanisms, potentially leading to advancements in the field.
Used in Material Development:
C-(4-PHENYL-MORPHOLIN-2-YL)-METHYLAMINE's properties also extend its utility to the development of new materials, where it may contribute to the creation of innovative substances with unique characteristics and applications across different industries.

Check Digit Verification of cas no

The CAS Registry Mumber 112913-99-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,9,1 and 3 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 112913-99:
(8*1)+(7*1)+(6*2)+(5*9)+(4*1)+(3*3)+(2*9)+(1*9)=112
112 % 10 = 2
So 112913-99-2 is a valid CAS Registry Number.

112913-99-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (4-phenylmorpholin-2-yl)methanamine

1.2 Other means of identification

Product number -
Other names C-(4-PHENYL-MORPHOLIN-2-YL)-METHYLAMINE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:112913-99-2 SDS

112913-99-2Downstream Products

112913-99-2Relevant articles and documents

Novel benzamides as selective and potent gastrokinetic agents. III. Synthesis and structure-activity relationships of 4-amino-5-chloro-2-methoxy- and 2-ethoxy-N-[(4-substituted 2-morpholinyl)methyl]-benzamides

Kato,Morie,Harada,Yoshida,Matsumoto

, p. 652 - 660 (2007/10/02)

A series of 4-amino-5-chloro-2-methoxy- and 2-ethoxy-N-[(4-substituted 2-morpholinyl)methyl]benzamides (11-44) were prepared and evaluated for gastrokinetic activity by determining their effects on the gastric emptying of phenol red semisolid meal in rats. The N-4 substituent includes alkyl, phenoxyalkyl, (4-fluorobenzoyl)alkyl, and heteroarylmethyl groups. The benzamide derivatives, having an isopropyl, isoamyl, neopentyl, 3-(4-chlorophenoxy)propyl, or pyridylmethyl group at N-4, showed potent in vivo gastric emptying activity. In particular, 4-amino-5-chloro-2-ethoxy-N-[[4-(3-pyridylmethyl)-2-morpholinyl]methyl ]benzamide (57b) was equipotent to the 4-fluorobenzyl analogue 1b (AS-4370 as its citrate) in the gastrokinetic activity on phenol red semisolid meal in rats and mice, and on resin pellet solid meal in rats. Moreover, compound 57b was free from dopamine D2 receptor antagonistic activity in both in vitro ([3H]spiperone binding) and in vivo (apomorphine-induced emesis in dogs) tests. Structure-activity relationships of compounds with various substituents at N-4 are also discussed.

Substituted benzamide derivatives, for enhancing gastrointestinal motility

-

, (2008/06/13)

Compounds of the formula: STR1 wherein R is hydrogen, alkoxycarbonyl, benzyloxycarbonyl, heteroarylalkyl, phenylalkenyl, or --T--(Y)p --R6 (wherein T is single bond or alkylene, Y is oxygen, sulfur or carbonyl, R6 is phenyl, substituted phenyl, naphthyl, or diphenylmethyl, and p is 0 or 1, provided that when T is single bond, p is 0); R1 is halogen, hydroxy, alkoxy, cycloalkyloxy, alkenyloxy, alkynyloxy, alkoxy interrupted by oxygen or carbonyl, alkylthio, amino, monosubstituted amino, or a substituted alkoxy; R2 is hydrogen; R3 is hydrogen, halogen, amino, alkylamino, dialkylamino, alkanoylamino, or nitro; R4 is hydrogen, halogen, nitro, sulfamoyl, alkylsulfamoyl, or dialkylsulfamoyl; or any two adjacent groups of the R1, R2, R3 and R4 may combine to form alkylenedioxy, and the remaining two groups are each hydrogen; R5 is hydrogen or alkyl; X is alkylene; m and n are each 1 or 2; provided that at least one of the groups R2, R3 and R4 is other than hydrogen, and acid addition salts, quaternary ammonium salts and N-oxide derivatives thereof, processes for preparation thereof, and pharmaceutical composition containing the same. Said compounds, salts and N-oxide derivatives thereof show excellent gastrointestinal motility enhancing activity.

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