112917-35-8

Upstream product

• 186581-53-3 diazomethane 
• 124601-86-1 (Z)-7-((2R,3R)-3-Benzenesulfonylamino-bicyclo[2.2.2]oct-2-yl)-hept-5-enoic acid 
• 4514-89-0 bicyclo<2.2.2>octanone oxime 
• 2716-23-6 bicyclo[2.2.2]octan-2-one 
• 112918-20-4 (2R,3R)-3-Allyl-bicyclo[2.2.2]oct-2-ylamine 
• 112918-19-1 3-Allyl-bicyclo[2.2.2]octan-2-one oxime 
• 112918-21-5 N-((2R,3R)-3-Allyl-bicyclo[2.2.2]oct-2-yl)-benzenesulfonamide 
• 112918-23-7 N-[(2R,3R)-3-(2-Oxo-ethyl)-bicyclo[2.2.2]oct-2-yl]-benzenesulfonamide 

Relevant academic research and scientific papers

SYNTHESIS OF MONOCYCLIC ANALOGUES OF A POTENT THROMBOXANE RECEPTOR ANTAGONIST, (+/-)-(5Z)-7-BICYCLOHEPT-2-EXO-YL>HEPTENOIC ACID (S-145)

Several monocyclic analogues of the potent thromboxane-A2 receptor antagonist S-145, i.e. cyclohexane, cyclopentane, tetrahydrofuran, and pyrrolidine, as well as the biclooctane one were synthesized using allylation via oxime dianion and the Barton's method for oxime reduction in the key steps.