112919-53-6

Basic information

• Product Name: 4,7'-dimethyl-3',4'-dihydrospiro(cyclohexane-1,3'-{2'H}-[1,3]thiazolo[3,2-b][1,2,4,5]tetraazin)-6'(7'H)-one
• Synonyms: 4,7'-dimethyl-3',4'-dihydrospiro(cyclohexane-1,3'-{2'H}-[1,3]thiazolo[3,2-b][1,2,4,5]tetraazin)-6'(7'H)-one
• CAS NO: 112919-53-6
• Molecular Formula: C11H18N4OS
• Molecular Weight: 254.35182
• Mol File: 112919-53-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4,7'-dimethyl-3',4'-dihydrospiro(cyclohexane-1,3'-{2'H}-[1,3]thiazolo[3,2-b][1,2,4,5]tetraazin)-6'(7'H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4,7'-dimethyl-3',4'-dihydrospiro(cyclohexane-1,3'-{2'H}-[1,3]thiazolo[3,2-b][1,2,4,5]tetraazin)-6'(7'H)-one(112919-53-6)
• EPA Substance Registry System: 4,7'-dimethyl-3',4'-dihydrospiro(cyclohexane-1,3'-{2'H}-[1,3]thiazolo[3,2-b][1,2,4,5]tetraazin)-6'(7'H)-one(112919-53-6)

Safety Data

• Hazardous Substances Data: 112919-53-6(Hazardous Substances Data)

Upstream product

• 112919-48-9 4-methyl-7,8,10,11-tetraazaspiro<5,5>undecane-9-thione 
• 598-72-1 2-Bromopropionic acid 

Relevant articles and documents

Heterocyclic Systems Containing Bridgehead Nitrogen Atom: Synthesis and Antimicrobial Activities of Spiro-thiazolo-s-tetrazine> Analogs

Synthesis of the spiro-thiazolo-s-tetrazine>analogs IIa, b, c and e has been achieved in a single step by treating 1,2,4,5-tetraazaspiroundecane-3-thione(Ia), 1,2,4,5-tetraazaspirododecane-3-thione (Ib), 1,2,4,5-tetraazaspirotridecane-3-thione (Ic) and 9-methyl-1,2,4,5-tetraazaspiroundecane-3-thione (Id) respectively with α-bromopropionic acid.The reaction of Id with chloroacetic acid results in the facile synthesis of 4-methyl-6'(7'H)-oxospiro-thiazolo-s-tetrazine> (IId). 7-Arylidene derivatives (III) have been prepared by condensation of IId with ald ehydes as well as by reaction of Id with ethyl chloroacetate and aldehydes in a single step.The structures II and III have been established by IR and PMR spectral data.The antibacterial and antifungal activities of II and III have been determined.