112921-88-7

Basic information

• Product Name: Ethanone, 1-[4-(1-propynyl)phenyl]- (9CI)
• Synonyms: Ethanone, 1-[4-(1-propynyl)phenyl]- (9CI)
• CAS NO: 112921-88-7
• Molecular Formula: C₁₁H₁₀O
• Molecular Weight: 158.1965
• Product Categories: ACETYLGROUP
• Mol File: 112921-88-7.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ethanone, 1-[4-(1-propynyl)phenyl]- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[4-(1-propynyl)phenyl]- (9CI)(112921-88-7)
• EPA Substance Registry System: Ethanone, 1-[4-(1-propynyl)phenyl]- (9CI)(112921-88-7)

Safety Data

• Hazardous Substances Data: 112921-88-7(Hazardous Substances Data)

Upstream product

• 13329-40-3 4-Iodoacetophenone 
• 58335-31-2 1,3-dilithiopropyne 
• 614-45-9 tert-Butyl peroxybenzoate 
• 42472-69-5 4-ethynylacetophenone 
• 590-93-2 2-Butynoic acid 
• 99-90-1 para-bromoacetophenone 
• 5633-34-1 (benzoylmethylene)dimethylsulfurane 
• 74-99-7 prop-1-yne 
• 99-91-2 para-chloroacetophenone 
• 64099-82-7 1-propynyltributylstannane 

Downstream Products

• 1352848-00-0 (E)-1-(4-(4-hydroxydodec-2-en-3-yl)phenyl)ethanone 
• 1352849-47-8 (E)-2-(3-(4-acetylphenyl)-2-hydroxypent-3-enyl)-isoindoline-1,3-dione 
• 1352848-76-0 (E)-1-(4-(5-(benzyloxy)-4-hydroxypent-2-en-3-yl)phenyl)ethanone 
• 1352850-34-0 (E)-1-(4-(1-hydroxy-1-phenylbut-2-en-2-yl)phenyl)ethanone 

Relevant articles and documents

Regiospecific palladium-catalyzed cross-coupling reactions using the operational equivalent of 1,3-dilithiopropyne

A regiospecific palladium-catalyzed cross-coupling reaction using the operational equivalent of the dianion 1,3-dilithiopropyne, with aromatic iodides is reported. This reaction gives high yields of 1-propyn-1-yl-benzenes and 2-(propyn-1-yl)thiophenes in

Enantioselective Addition of α-Nitroesters to Alkynes

By using Rh–H catalysis, we couple α-nitroesters and alkynes to prepare α-amino-acid precursors. This atom-economical strategy generates two contiguous stereocenters, with high enantio- and diastereocontrol. In this transformation, the alkyne undergoes isomerization to generate a RhIII–π-allyl electrophile, which is trapped by an α-nitroester nucleophile. A subsequent reduction with In powder transforms the allylic α-nitroesters to the corresponding α,α-disubstituted α-amino esters.

Controlled Single and Double Iodofluorination of Alkynes with DIH- and HF-Based Reagents

A novel protocol for the regio- and stereoselective iodofluorination of internal and terminal alkynes using 1,3-diiodo-5,5,-dimethylhydantoin and HF-based reagents is disclosed. This approach is used to prepare a fluorinated tamoxifen derivative in two steps from commercially available starting materials. A facile method enabling controlled regioselective double iodofluorination of terminal alkynes is also presented.