112922-55-1

Basic information

• Product Name: Cericlamine
• Synonyms: Cericlamine;Cericlamine [inn];Unii-ves82D23ib
• CAS NO: 112922-55-1
• Molecular Formula: C12H17Cl2NO
• Molecular Weight: 262.178
• Mol File: 112922-55-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 362°Cat760mmHg
• Flash Point: 172.8°C
• Appearance: /
• Density: 1.208g/cm³
• Vapor Pressure: 7.1E-06mmHg at 25°C
• Refractive Index: 1.552
• CAS DataBase Reference: Cericlamine(CAS DataBase Reference)
• NIST Chemistry Reference: Cericlamine(112922-55-1)
• EPA Substance Registry System: Cericlamine(112922-55-1)

Safety Data

• Hazardous Substances Data: 112922-55-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H17Cl2NO/c1-12(8-16,15(2)3)7-9-4-5-10(13)11(14)6-9/h4-6,16H,7-8H2,1-3H3

Upstream product

• 18880-04-1 3,4-dichlorobenzyl bromide 
• 102-47-6 3,4-Dichlorophenylmethyl chloride 
• 1393737-32-0 diethyl (S)-2-(3,4-dichlorobenzyl)-2-((α-methylbenzyl)amino)malonate hydrochloride 
• 1393737-51-3 (S)-[4-(3,4-dichlorobenzyl)-2-oxazolidinon-4-yl]methyl p-toluenesulfonate 
• 1393737-48-8 (R)-4-(3,4-dichlorobenzyl)-4-hydroxymethyl-2-oxazolidinone 
• 1393737-41-1 (4R,αS)-4-(3,4-dichlorobenzyl)-4-hydroxymethyl-3-(α-methylbenzyl)-2-oxazolidinone 
• 1393737-38-6 (S)-2-(3,4-dichlorobenzyl)-2-((α-methylbenzyl)amino)-1,3-propanediol 
• 1393737-34-2 diethyl (S)-2-(3,4-dichlorobenzyl)-2-((α-methylbenzyl)amino)malonate 
• 50-00-0 formaldehyd 
• 112964-25-7 (S)-3-(3,4-dichlorophenyl)-2-methyl-2-methylamino-1-propanol 
• 112922-60-8 (S)-2-amino-2-(3,4-dichlorobenzyl)-1-propanol 
• 112922-58-4 (S)-2-amino-3-(3,4-dichlorophenyl)-2-methylpropan-1-ol 
• 112922-43-7 (S)-(-)-2-amino-2(3,4-dichlorobenzyl)-1-propanol 

Related news

Effects of acute and chronic treatment with amoxapine and Cericlamine (cas 112922-55-1) on the sleep-wakefulness cycle in the rat07/26/2019

Antidepressant drugs, such as the tricyclics and the serotonin reuptake inhibitors, are well known to decrease paradoxical sleep and occasionally increase slow wave sleep in human and in animals. In order to examine whether amoxapine (a mixed NA reuptake blocker and 5-HT2/5-HT3 antagonist) and c...detailed

Relevant articles and documents

Synthesis of (S)-(+)-cericlamine through lipase-catalyzed aminolysis of azo acetates

The kinetic enzymatic resolution of azo acetates via aminolysis with Candida antarctica lipase B has been investigated using benzylamine as amine component. The products obtained from this biotransformation in high enantiomeric purity can serve as valuable precursors for various amino alcohols, as exemplified by the synthesis of the serotonin reuptake inhibitor (S)-(+)-cericlamine.

Process for the preparation of (+/-)3-(3,4-dichlorophenyl)-2-dimethylamino-2-methylpropan-1-OL or cericlamine (INN)

PCT No. PCT/EP98/02213 Sec. 371 Date Dec. 20, 1999 Sec. 102(e) Date Dec. 20, 1999 PCT Filed Apr. 6, 1998 PCT Pub. No. WO98/45248 PCT Pub. Date Oct. 15, 1998Process for the preparation of cericlamine which consists: i) in arylating methacrylic acid with th

Chemo-Enzymatic Synthesis of (S)-(+)-Cericlamine and Related Enantiomerically Pure 2,2-Disubstituted-2-aminoethanols

The synthesis of (S)-(+)-cericlamine (S)-1 and related disubstituted amino alcohols is described as an example of the stereoselective synthesis of amino alcohols from disubstituted amino acids and their corresponding amides.Thus, the amino alcohols (S)-1,