112925-36-7

Usage

Uses

Used in Pharmaceutical Industry:
1-(4-benzyl-1,4-oxazepan-2-yl)methanamine(SALTDATA: FREE) is used as a pharmaceutical compound for its potential therapeutic effects, leveraging its unique structure to target specific biological pathways or receptors.
Used in Organic Synthesis:
In the field of organic synthesis, 1-(4-benzyl-1,4-oxazepan-2-yl)methanamine(SALTDATA: FREE) serves as a reagent, contributing to the formation of complex organic molecules for various applications, including the development of new drugs and materials.
Used in Industrial Processes:
1-(4-benzyl-1,4-oxazepan-2-yl)methanamine(SALTDATA: FREE) may also be utilized in other industrial processes, where its chemical properties can be harnessed for specific technical or manufacturing purposes, depending on its salt form and any accompanying data.

Upstream product

• 309747-68-0 3-[Benzyl-(3-chloro-2-hydroxy-propyl)-amino]-propan-1-ol 
• 129482-45-7 4-benzyl-2-chloromethyl-[1,4]oxazepane 
• 4720-29-0 3-(benzylamino)propan-1-ol 
• 129482-46-8 4-benzyl-2-(phthalimidomethyl)hexahydro-1,4-oxazepine 

Downstream Products

• 1184662-16-5 2-acetylaminomethyl-4-benzyl-1,4-hexahydroxazepine 

Relevant academic research and scientific papers

Development of potent serotonin-3 (5-HT3) receptor antagonists. I. Structure-activity relationships of 2-alkoxy-4-amino-5-chlorobenzamide derivatives

A new series of 2-alkoxy-4-amino-5-chlorobenzamide derivatives hearing five- to seven-membered heteroalicyclic rings in the amine moiety was synthesized and evaluated for serotonin-3 (5-HT3) receptor antagonistic activity by assaying the ability to antagonize the yon Bezold-Jarisch reflex in rats. The five- to seven-membered heteroalicycles comprise pyrrolidine, morpholine, 1,4-thiazine, piperidine, piperazine, 1,4-oxazepine, 1,4- thiazepine, azepine, and 1,4-diazepine rings. Among them, some benzamide derivatives having a 1,4-diazepine ring showed a potent 5-HT3 receptor antagonistic activity. In particular, 4-amino-5-chloro-N-(1,4- dimethylhexahydro-1H-1,4-diazepin-6-yl)-2-ethoxyhenzamide (96) and the 1- benzyl-4-methylhexahydro-1H-1,4-diazepine analogue 103 showed potent 5-HT3 receptor antagonistic activity without 5-HT4 receptor binding affinity.

Quinolone antimicrobial agents substituted with morpholines at the 7- position. Syntheses and structure-activity relationships

A series of novel 7-substituted 1-cyclopropyl-6,8-difluoro-1,4-dihydro-4- oxo-3-quinolinecarboxylic acids have been prepared and tested for antibacterial activities and for convulsive activities in combination with nonsteroidal antiinflammatory drug. Stru

Substituted benzamide derivatives, for enhancing gastrointestinal motility

Compounds of the formula: STR1 wherein R is hydrogen, alkoxycarbonyl, benzyloxycarbonyl, heteroarylalkyl, phenylalkenyl, or --T--(Y)p --R6 (wherein T is single bond or alkylene, Y is oxygen, sulfur or carbonyl, R6 is phenyl, substituted phenyl, naphthyl, or diphenylmethyl, and p is 0 or 1, provided that when T is single bond, p is 0); R1 is halogen, hydroxy, alkoxy, cycloalkyloxy, alkenyloxy, alkynyloxy, alkoxy interrupted by oxygen or carbonyl, alkylthio, amino, monosubstituted amino, or a substituted alkoxy; R2 is hydrogen; R3 is hydrogen, halogen, amino, alkylamino, dialkylamino, alkanoylamino, or nitro; R4 is hydrogen, halogen, nitro, sulfamoyl, alkylsulfamoyl, or dialkylsulfamoyl; or any two adjacent groups of the R1, R2, R3 and R4 may combine to form alkylenedioxy, and the remaining two groups are each hydrogen; R5 is hydrogen or alkyl; X is alkylene; m and n are each 1 or 2; provided that at least one of the groups R2, R3 and R4 is other than hydrogen, and acid addition salts, quaternary ammonium salts and N-oxide derivatives thereof, processes for preparation thereof, and pharmaceutical composition containing the same. Said compounds, salts and N-oxide derivatives thereof show excellent gastrointestinal motility enhancing activity.