112929-13-2

Upstream product

• 112929-12-1 1-phthalimido-6-tetrahydropyranyloxy-2-hexene 
• 80307-08-0 2,6-dimethyl-3,5-bis(methoxycarbonyl)-4-(3-methylphenyl)-1,4-dihydropyridine 

Downstream Products

• 112929-14-3 1,4-dihydro-2,6-dimethyl-4-(3-methylphenyl)-3,5-pyridine dicarboxylic acid, 3-(6-aminohex-4-enyl)-5-methyl ester 

Relevant academic research and scientific papers

1,4-dihydropyridines

This invention provides compounds useful for treating coronary insufficiency, hypertension, angina pectoris, cardiac arrythmia, heart attack or coronary vasospasm and represented by the general formula: STR1 R1 and R2 are each independently selected from the group consisting of lower alkyl, N-alkylphthalimido and derivatives of N-alkylphthalimido, wherein said N-alkyl group comprises at least 2 carbon atoms; A is a straight or branched chain hydrocarbon moiety containing from 1 to 12 carbon atoms and from 0 to 2 double bonds; R3 is selected from the group of radicals consisting of hydrogen, --NH2 and --NCS; R4 is an aryl or heteroaryl radical; and R5 is a lower alkyl radical or A--R3 ; provided that when R3 is a hydrogen radical at least one of R1 and R2 is not lower alkyl, including both pure enantiomers as well as mixtures thereof; and pharmaceutically-acceptable salts thereof.