112929-89-2

Basic information

• Product Name: 3-Bromo-1-methylnaphthalene
• Synonyms: 3-Bromo-1-methylnaphthalene
• CAS NO: 112929-89-2
• Molecular Formula: C₁₁H₉Br
• Molecular Weight: 221.09316
• Mol File: 112929-89-2.mol
• Article Data: 5

Chemical Properties

• Melting Point: 46-47 °C
• Boiling Point: 302.1±11.0 °C(Predicted)
• Appearance: /
• Density: 1.417±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 3-Bromo-1-methylnaphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromo-1-methylnaphthalene(112929-89-2)
• EPA Substance Registry System: 3-Bromo-1-methylnaphthalene(112929-89-2)

Safety Data

• Hazardous Substances Data: 112929-89-2(Hazardous Substances Data)

Usage

General Description

3-Bromo-1-methylnaphthalene is a chemical compound with the molecular formula C11H9Br. It is a brominated derivative of 1-methylnaphthalene, which is commonly used in the synthesis of pharmaceuticals and agrochemicals. 3-Bromo-1-methylnaphthalene is a pale yellow solid with a strong aromatic odor. It is primarily used as an intermediate in the production of organic compounds, such as dyes and pigments. This chemical is toxic if inhaled, swallowed, or in contact with skin, and it may cause respiratory irritation if inhaled. It is also harmful to aquatic life with long-lasting effects, so it should be handled and disposed of with caution.

Upstream product

• 51670-78-1 1-acetamido-4-methylnaphthalene 
• 4523-45-9 1-amino-4-methylnaphthalene 
• 112929-88-1 1-amino-2-bromo-4-methylnaphthalene 
• 4523-46-0 4-methyl-2-naphthalenamine 

Downstream Products

• 112929-90-5 3-cyano-1-methylnaphthalene 
• 303779-66-0 3-bromo-1-naphthaldehyde 
• 303063-43-6 (2R,3S,5R)-2-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-3-(4-methoxy-benzyloxy)-5-(4-methyl-naphthalen-2-yl)-tetrahydro-furan 

Relevant articles and documents

Pyrrole derivatives useful for farnesyl transferase inhibitors and their preparations

The present invention relates to a novel pyrrole derivative which shows an inhibitory activity against farnesyl transferase or pharmaceutically acceptable salts or isomers thereof; to a process for preparation of said compound; and to a pharmaceutical composition such as anti-cancer composition, etc. comprising said compound as an active ingredient together with pharmaceutically acceptable carrier.

Preparation of biaryl compounds

A method for the preparation of biaryl compounds is disclosed which comprises contacting an aryl halide with a tertiary-alkyl organometallic reagent (or the precursor components thereof) in the presence of a catalyst comprising a nickel compound and a coordinating ligand under conditions suitable for the formation of biaryl compound. In an alternative embodiment of the present invention, nickel(0) compounds are prepared from nickel(II) compounds by contacting a nickel(II) compound with a combination of an organophosphine and a bidentate nitrogen-containing coordinating ligand, and a tertiary-alkyl organometallic reagent (or the precursor components thereof) in an aprotic, non-polar, ether-containing solvent system for a time and under conditions suitable for the formation of nickel(0) compound.

Substituent effects on homolytic versus heterolytic photocleavage of (1-naphthylmethyl)trimethylammonium chlorides

Singlet escited state rate constants have been measured for both the heterolytic and homolytic photocleavage of 3- and 4-methoxy and 3- and 4-cyano (1-naphthylmethyl)trimethylammonium chlorides, 6-10.The results are interpreted in terms of the meta effect or changes in charge distribution upon excitation and the competition between bond cleavage, electron transfer, and hydrogen atom transfer in the contact pairs resulting from the two types of cleavage.