112940-54-2

Upstream product

• 125818-95-3 N-<4-<4-(phenylmethyl)piperazin-1-yl>phenyl>methanesulfonamide 
• 125818-67-9 N-<4-<4-(phenylmethyl)piperazin-1-yl>phenyl>methanesulfonamide 1.2-hydrochloride 

Downstream Products

• 128263-90-1 N-[4-[4-(2-hydroxy-3-phenoxypropyl)piperazin-1-yl]phenyl]methanesulfonamide 
• 128263-91-2 N-{4-[4-(3-Dicyclopropylmethyleneaminooxy-2-hydroxy-propyl)-piperazin-1-yl]-phenyl}-methanesulfonamide 
• 128263-99-0 N-[4-[4-[2-hydroxy-3-[4-(2-methoxyethyl)phenoxy]propyl]piperazin-1-yl]phenyl]methanesulfonamide 
• 128263-95-6 N-[4-[4-[2-hydroxy-3-(2-methylphenoxy)propyl]piperazin-1-yl]phenyl]methanesulfonamide 
• 129872-59-9 N-(4-{2-Hydroxy-3-[4-(4-methanesulfonylamino-phenyl)-piperazin-1-yl]-propoxy}-phenyl)-acetamide 
• 128263-97-8 N-[4-[4-[2-hydroxy-3-[(5,6,7,8-tetrahydro-5-oxo-1-naphthalenyl)oxyl]propyl]-1piperazinyl]phenyl]methanesulfonamide 
• 128263-93-4 N-[4-[4-[2-hydroxy-3-(3-methylphenoxy)propyl]piperazin-1-yl]phenyl]methanesulfonamide 

Relevant academic research and scientific papers

Derivatized alkanolamines as cardiovascular agents

Novel derivatized alkanolamines of the following structural formula STR1 are described as useful cardiovascular agents. Most especially described is their usefulness as cardiovascular agents exhibiting an antiarrhythmic effect. Said antiarrhythmic effect is of a combination Class II/Class III variety. Pharmaceutical formulations containing such compounds are also described.

Novel N-[4-(aminosubstituted)phenyl]methanesulfonamides and their use as cardiovascular agents

Novel N-[4-(aminosubstituted)phenyl]methanesulfonamides and their use as cardiovascular agents, especially as antiarrhythmic agents are described. Pharmaceutical formulations containing such compounds are also discussed.

Synthesis of novel (aryloxy)propanolamines and related compounds possessing both class II and class III antiarrhythmic activity

Several (aryloxy)propanolamines and related compounds (i.e. 5-13, 16-18, 20-24, 27-33, 35, 37-39, 41, and 42) were synthesized and investigated for their class III electrophysiological activity and class II (β-blocking) effects with use of in vitro and in

4-Substituted-1-(4-alkylsulphonamidophenyl)piperazines as antiarrhythmic agents

Antiarrhythmic agents of the formula: STR1 and their pharmaceutically acceptable salts, wherein R and R1, which are the same or different, are C1 -C4 alkyl, C3 -C7 cycloalkyl, --CH2 CH

Phenyl piperazine anti-arrhythmia agents

A series of pyridyl or imidazolyl substituted phenyl piperazines having utility as anti-arrhythmic agents is disclosed.