112947-93-0

Basic information

• Product Name: 2-(BENZOIMIDAZOLE-1-YL)-ETHYLAMINE
• Synonyms: 2-(BENZOIMIDAZOLE-1-YL)-ETHYLAMINE;2-(1H-benzo[d]imidazol-1-yl)ethanamine;2-(1H-1H-benzo[d]iMidazol-1-yl)ethanaMine
• CAS NO: 112947-93-0
• Molecular Formula: C₉H₁₁N₃*2ClH
• Molecular Weight: 161.2
• Mol File: 112947-93-0.mol
• Article Data: 1

Chemical Properties

• Melting Point: 280 °C
• Appearance: /
• CAS DataBase Reference: 2-(BENZOIMIDAZOLE-1-YL)-ETHYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(BENZOIMIDAZOLE-1-YL)-ETHYLAMINE(112947-93-0)
• EPA Substance Registry System: 2-(BENZOIMIDAZOLE-1-YL)-ETHYLAMINE(112947-93-0)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 112947-93-0(Hazardous Substances Data)

Usage

General Description

2-(benzoimidazole-1-yl)-ethylamine is a chemical compound that consists of a benzoimidazole ring attached to an ethylamine group. It is a small molecule that has potential biological and pharmacological activity due to its structural features. The compound can be used in medicinal chemistry research for the development of new drugs and pharmaceuticals. It may also have applications in the field of organic synthesis and chemical biology as a building block or intermediate for the preparation of more complex molecules. Overall, 2-(benzoimidazole-1-yl)-ethylamine is a versatile chemical with diverse potential uses in various scientific and industrial applications.

Upstream product

• 86419-71-8 N-(2-nitrophenyl)ethylenediamine hydrochloride 

Downstream Products

• 1442462-79-4 2-(2-(1H-benzimidazol-2-yl-ethylimino)methyl)-4-methylphenol 
• 905969-63-3 2-[(2-(1H-benzo[d]-imidazol-2-yl)ethylimino)methyl]phenol 

Relevant articles and documents

Arylalkylamine-, β-carboline-, quinolizine- and azecine-derived compounds and their in vitro interaction with the ionotropic 5-HT3 receptor: Search for new lead structures

Specific serotonin receptor agonists and antagonists are marketed with respect to various diseases, most prominently severe emesis. To identify new chemical classes with affinity for the serotonin 5-HT3 channel, several compounds were synthesized which can be structurally classified as arylalkylamines, azecines, quinolizines and β-carbolines. These were tested in three models: 1. direct effect on ileum (overall model for contracting or relaxant effect), 2. antiserotoninergic effects on rat ileum (crude serotonin model), 3. inhibitory effect on the 5-HT3 receptor channel complex expressed in N1E-115 cells (serotonin-induced [14C]guanidinium influx (specific model)). Key findings and conclusion: Several azecine-type compounds exhibit 5-HT3 receptor channel antagonistic properties at concentrations close to that of tropisetron (used as a positive control) and might serve as potential lead structures for the development of further 5-HT3 channel receptor antagonists. ECV · Editio Cantor Verlag.