112953-99-8

Basic information

• Product Name: 4H-1-Benzopyran-4-one, 5-chloro-7-hydroxy-3-(2-phenylethyl)-
• CAS NO: 112953-99-8
• Molecular Formula: C17H13ClO3
• Molecular Weight: 300.741
• Mol File: 112953-99-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4H-1-Benzopyran-4-one, 5-chloro-7-hydroxy-3-(2-phenylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1-Benzopyran-4-one, 5-chloro-7-hydroxy-3-(2-phenylethyl)-(112953-99-8)
• EPA Substance Registry System: 4H-1-Benzopyran-4-one, 5-chloro-7-hydroxy-3-(2-phenylethyl)-(112953-99-8)

Safety Data

• Hazardous Substances Data: 112953-99-8(Hazardous Substances Data)

Upstream product

• 18496-54-3 phenylbutyric acid chloride 
• 7051-16-3 1-chloro-3,5-dimethoxybenzene 
• 139027-41-1 5-Chloro-7-methoxy-3-phenethyl-chromen-4-one 

Downstream Products

• 112953-84-1 (5-Chloro-4-oxo-3-phenethyl-4H-chromen-7-yloxy)-acetic acid ethyl ester 
• 112953-65-8 (5-Chloro-4-oxo-3-phenethyl-4H-chromen-7-yloxy)-acetic acid 

Relevant articles and documents

Aryloxyacetic acid diuretics with uricosuric activity. II. Substituted [(4-oxo-4H-1-benzopyran-7-yl)oxy]acetic acids and the related compounds

Di- and tri-substituted [(4-oxo-4H-1-benzopyran-7-yl)oxy]acetic acids, and 4-oxo-3-phenyl-4H-furo[2,3-h][1]benzopyran-8-carboxylic acid were synthesized and tested for natriuretic and uricosuric activities. Among the compounds tested, 3,5-disubstituted [(4-oxo-4H-1-benzopyran-7-yl)oxy]acetic acids (6c-f, h, n and x) showed potent natriuretic and uricosuric activities, whereas 4-oxo-3-phenyl-4H-furo[2,3-h][1]benzopyran-8-carboxylic acid (6dd) possessed only potent natriuretic activity. The structure-activity relationships are also discussed.