112966-96-8Relevant articles and documents
Enantioselective synthesis of S-1452, an orally active potent thromboxane A2 receptor antagonist
Ohtani,Matsuura,Watanabe,Narisada
, p. 2122 - 2127 (2007/10/02)
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Synthesis and in vitro activity of stereoisomers of a novel thromboxane receptor antagonist, (±)-(5Z)-7-[3-endo-[(phenylsulfonyl)amino]bicyclo[2.2.1]hept-2-exo-yl ]heptenoic acid
Ohtani,Narisada
, p. 1027 - 1031 (2007/10/02)
Three stereoisomers of S-145 (1) with variations at the side-chain junctions were synthesized. Endo-cis-isomer 10 and N-exo-trans isomer 18 were obtained via the common intermediate 5 having an endo-fused ring structure. Exo-cis isomer 28 was prepared via