1129683-88-0 Usage
Uses
Used in Cardiovascular Medicine:
Ticagrelor is used as an antiplatelet agent for the prevention of blood clots in patients with acute coronary syndrome or a history of heart attack. It inhibits the P2Y12 receptor on platelets, reducing their ability to clump together and form clots, thus lowering the risk of cardiovascular events such as heart attack and stroke.
Used in Combination Therapy:
Ticagrelor is often used in combination with aspirin, a nonsteroidal anti-inflammatory drug, to provide a dual antiplatelet effect. This combination therapy enhances the prevention of blood clot formation and reduces the risk of cardiovascular events in patients with the aforementioned conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 1129683-88-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,2,9,6,8 and 3 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1129683-88:
(9*1)+(8*1)+(7*2)+(6*9)+(5*6)+(4*8)+(3*3)+(2*8)+(1*8)=180
180 % 10 = 0
So 1129683-88-0 is a valid CAS Registry Number.
1129683-88-0Relevant academic research and scientific papers
Process for the Preparation of a RAF Kinase Inhibitor and Intermediates for Use in the Process
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Page/Page column 22, (2010/12/29)
There is provided a process for preparing sorafenib or a salt thereof comprising the use of a compound of formula (A) wherein R′ is selected from the group consisting of hydrogen, —C(O)OA, —C(O)CX3, —C(O)NH2, —C(O)—NHOH or There is also provided intermediate compounds of general formula (A), N-methyl-4-(4-ureidophenoxy)picolinamide, 4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenylcarbamate derivative and N-methyl-4-(4-(2,2,2-trihaloacetamido)phenoxy)picolinamide, processes for their preparation and their use in the preparation of sorafenib.
