1129697-15-9

Upstream product

• 5781-53-3 monomethyl oxalyl chloride 
• 1129697-37-5 C₂₄H₂₃NO₃ 
• 696-62-8 para-iodoanisole 
• 170238-94-5 3,4-bis(4-methoxyphenyl)-1H-pyrrole-2-carboxylic acid methyl ester 
• 3179-10-0 1-methoxy-4-(2-nitro-vinyl)-benzene 
• 59019-40-8 1-[(1Z)-2-bromo-2-nitroethenyl]-4-methoxybenzene 
• 1337927-65-7 (E)-4,4'-(1-nitroethene-1,2-diyl)bis(4-methoxybenzene) 
• 2132-62-9 4,4'-dimethoxydiphenylacetylene 
• 108180-11-6 methyl 2-(methyleneamino)-acetate 
• 556812-41-0 4-methoxy-2-(trimethylsilyl)phenyl triflate 
• 104-94-9 4-methoxy-aniline 
• 5703-26-4 4-Methoxyphenylacetaldehyde 
• 1261079-23-5 C₂₆H₂₃NO₅ 
• 18107-18-1 diazomethyl-trimethyl-silane 

Relevant academic research and scientific papers

Domino Reaction for the Synthesis of Polysubstituted Pyrroles and Lamellarin R

A three-component annulation reaction was developed for the synthesis of pyrroles, a class of compounds with various properties valuable to biomedical and polymer industries. Treatment of α-silylaryl triflates, Schiff bases, and alkynes generated polysubs

Synthesis of lamellarin R, lukianol A, lamellarin O and their analogues

Three lamellarin alkaloids type III (lamellarin R, lukianol A and lamellarin O) were synthesized using the Barton-Zard reaction as a key step to construct the central pyrrole core. Some of their corresponding 4-benzoyl and 5-phenyl substituted pyrrole ana

Synthesis of non-symmetrical 3,4-diaryl-substituted pyrroles: Implementation for the preparation of lamellarin R

A straightforward method for synthesising symmetrical and non-symmetrical 3,4-diaryl-substituted pyrroles is proposed, consisting of (i) the condensation reaction between phenylacetonitriles and aldehydes to give acrylonitriles, (ii) the conjugate additio

Total synthesis of lamellarins D, H, and R and ningalin B

A concise total synthesis of lamellarins D (7 steps), H (7 steps), and R (5 steps) and ningalin B (5 steps) is achieved starting from the corresponding aldehydes and amines. The synthesis features three oxidative reactions as key steps in a biomimetic manner, involving an AgOAc-mediated oxidative coupling reaction to construct the pyrrole core, a Pb(OAc)4-induced oxidative cyclization to form the lactone, and Kita's oxidation reaction to form the pyrrole-arene C-C bond.

A direct phosphine-mediated synthesis of pyrroles from acid chlorides and α,β-unsaturated imines

A one-step method to assemble pyrroles from α,β-unsaturated imines and acid chlorides has been developed. This reaction is mediated by triphenylphosphine, which eliminates phosphine oxide to allow cyclization. This reaction has been employed to access a d