112971-19-4

Basic information

• Product Name: 3-(1-PHENYLETHYLAMINO)PROPANENITRILE
• Synonyms: 3-(1-PHENYLETHYLAMINO)PROPANENITRILE;3-(1-Phenyl-ethylamino)-propionitrile
• CAS NO: 112971-19-4
• Molecular Formula: C₁₁H₁₄N₂
• Molecular Weight: 174.24
• Mol File: 112971-19-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 302.3 °C at 760 mmHg
• Flash Point: 136.6 °C
• Appearance: /
• Density: 0.997 g/cm³
• CAS DataBase Reference: 3-(1-PHENYLETHYLAMINO)PROPANENITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(1-PHENYLETHYLAMINO)PROPANENITRILE(112971-19-4)
• EPA Substance Registry System: 3-(1-PHENYLETHYLAMINO)PROPANENITRILE(112971-19-4)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 112971-19-4(Hazardous Substances Data)

Usage

General Description

3-(1-phenylethylamino)propanenitrile is a chemical compound with the molecular formula C11H14N2. It is also known as N-(3-cyanopropyl)phenylethylamine and is classified as an amphetamine derivative. 3-(1-PHENYLETHYLAMINO)PROPANENITRILE is a stimulant and psychoactive substance that affects the central nervous system. It is often described as a psychoactive or designer drug and has been associated with abuse and misuse. Its effects on the human body include increased heart rate, elevated blood pressure, and heightened alertness. 3-(1-phenylethylamino)propanenitrile is considered a controlled substance in many countries due to its potential for abuse and addiction.

Upstream product

• 107-13-1 acrylonitrile 
• 618-36-0 rac-methylbenzylamine 

Downstream Products

• 101783-39-5 N-(2-cyano-ethyl)-N'-phenyl-N-(1-phenyl-ethyl)-thiourea 

Relevant articles and documents

Chemoselective catalytic conjugate addition of alcohols over amines

A highly chemoselective conjugate addition of alcohols in the presence of amines is described. The cooperative nature of the catalyst enabled chemoselective activation of alcohols over amines, allowing the conjugate addition to soft Lewis basic α,β-unsaturated nitriles. Divergent transformation of the nitrile functionality highlights the utility of the present catalysis. The cooperative nature of a copper catalyst enabled the highly chemoselective activation of alcohols in the presence of amines and thus the conjugate addition of the hydroxy group to soft Lewis basic α,β-unsaturated nitriles. The presented method proceeds under proton-transfer conditions, reverses the innate reactivity of the OH and NH groups, and does not require protecting groups. dppe=1,2-bis(diphenylphosphino) ethane, MeSal=3-methylsalicylate. Copyright

RuCl3 in poly(ethylene glycol): A highly efficient and recyclable catalyst for the conjugate addition of nitrogen and sulfur nucleophiles

The 1,4-conjugate addition of primary, secondary and aromatic amines, thiols, and carbamate to α,β-unsaturated compounds mediated by a catalytic amount (0.5 mol%) of RuCl3 in poly(ethylene glycol) (PEG) provides the desired β-substituted carbonyls in high yields. In particular, we found that primary aliphatic and aromatic amines produced the single adducts as the sole products in very high yields with RuCl3-PEG. RuCl 3-PEG was readily recycled via solvent precipitation with efficient recyclability as evidenced by high yields. Its properties of low sensitivity toward moisture and oxygen, high tolerance of different functional groups, and efficient recyclability make RuCl3-PEG suitable for both laboratory and industrial scale synthesis of β-substituted carbonyls. Georg Thieme Verlag Stuttgart.

Indium trichloride-catalyzed conjugate addition of amines to α,β-ethylenic compounds in water

Catalytic amount of indium (III) trichloride efficiently catalyzed Michael reaction between amines and α,β-ethylenic compounds in water and under mild conditions. Indium trichloride can be recovered and reused without decrease in yield.