112995-86-5

Upstream product

• 102436-29-3 (2R,3R,4S)-3,4-O-dibenzylhex-5-ene-1,2,3,4-tetrol 

Downstream Products

• 112995-87-6 6,7-di-O-benzyl-1,3,4,5,8,9-hexadeoxy-L-erythro-non-4,8-dieno-2-ulose 
• 859844-71-6 (2R,5S,6R)-2-((1S,2S)-1,2-Bis-benzyloxy-but-3-enyl)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-5-methyl-[1,3]dioxan-4-one 
• 1175535-31-5 (4R,5R,6S)-5,6-bis(benzyloxy)oct-7-en-4-ol 
• 859844-69-2 (2R,3S,6R)-6-((1R,2S)-1,2-Bis-benzyloxy-but-3-enyl)-2-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-3-methyl-tetrahydro-pyran-4-one 

Relevant academic research and scientific papers

Total synthesis of phytotoxic herbarumin-I from d-mannitol

A simple carbohydrate-based convergent approach towards the total synthesis of herbarumin-I, a 10-membered lactone is described. The key features of the synthetic strategy include Grignard reaction and ring-closing metathesis reaction for the formation of the 10-membered ring and E-olefinic moiety. d-Mannitol has been used as a chiral pool material for the construction of the key fragment.

Chiral building units from carbohydrates-XIII. Identification of the absolute configuration of endo-brevicomin from dendroctonus frontalis and synthesis of both enantiomers from d-ribose

The synthesis of both enantiomers of endo-7-ethyl-5-methyl-6,8-dioxabicyclo[3.2.l]octana (endo-brevicomin, 12 and 12a) starting froni D-ri-bose is described. Key interinediate is the open chain derivative 7, a chiral building unit easily available from ca