113009-22-6

Basic information

• Product Name: {1-[3-(2,5-Dioxo-imidazolidin-4-yl)-propyl]-cyclohexyl}-acetonitrile
• Synonyms: {1-[3-(2,5-Dioxo-imidazolidin-4-yl)-propyl]-cyclohexyl}-acetonitrile
• CAS NO: 113009-22-6
• Molecular Weight: 263.34
• Mol File: 113009-22-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {1-[3-(2,5-Dioxo-imidazolidin-4-yl)-propyl]-cyclohexyl}-acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: {1-[3-(2,5-Dioxo-imidazolidin-4-yl)-propyl]-cyclohexyl}-acetonitrile(113009-22-6)
• EPA Substance Registry System: {1-[3-(2,5-Dioxo-imidazolidin-4-yl)-propyl]-cyclohexyl}-acetonitrile(113009-22-6)

Safety Data

• Hazardous Substances Data: 113009-22-6(Hazardous Substances Data)

Upstream product

• 113009-26-0 Toluene-4-sulfonic acid 1-pent-4-enyl-cyclohexylmethyl ester 
• 113009-27-1 1-(cyanomethyl)-1-(5-pent-1-enyl)cyclohexane 
• 113009-19-1 methyl 1-(5-pent-1-enyl)cyclohexanecarboxylate 
• 113009-20-4 1-(pent-4-en-1-yl)cyclohexylmethanol 
• 4630-82-4 methyl cyclohexylcarboxylate 
• 143-33-9 sodium cyanide 
• 506-87-6 ammonium carbonate 
• 113009-21-5 1-(cyanomethyl)-1-(3-formylpent-1-yl)cyclohexane 

Downstream Products

• 113009-17-9 2-amino-5-<1-(carboxymethyl)cyclohexyl>pentanoic acid 
• 113009-23-7 2-Boc-amino-5-[(1-carboxymethyl)cyclohexyl]pentanoic acid 
• 113009-18-0 2-(boc-amino)-5-<1-(carbobenzoxymethyl)cyclohexyl>pentanoic acid 
• 113009-24-8 benzyl 2-(boc-amino)-5-<(1-carbobenzoxymethyl)cyclohexyl>pentanoate 

Relevant articles and documents

Synthesis of 6,6-Pentamethylene-2-aminosuberic Acid. A Key Intermediate in the Synthesis of Dicarba Analogues of Vasopressin Antagonists

Two complementary syntheses of the unnatural amino acid, 6,6-cyclopentamethylene-2-aminosuberic acid, Pas (2) are described.The first, starting from methyl cyclohexanecarboxylate (4), yields in ten steps racemic Boc-Pas(OBzl)-OH (3) which is suitably protected for solid phase peptide synthesis.The second method involves the stereospecific synthesis of optically pure Boc-Pas(OBzl)-OH (3L) utilizing the electrochemical coupling, via the Kolbe method of the monobenzyl ester of 1,1-cyclohexanediacetic acid (13) and Boc-L-Glu-OBzl (14).The optical purity of 3L was confirmed by chiral gas chromatographic analysis of its N-pentafluoropropionyl diisopropyl ester derivative 15L.