1130165-68-2Relevant academic research and scientific papers
Design, synthesis, and structure-activity analysis of isoform-selective retinoic acid receptor β ligands
Lund, Birgitte W.,Knapp, Anne Eeg,Piu, Fabrice,Gauthier, Natalie K.,Begtrup, Mikael,Hacksell, Uli,Olsson, Roger
supporting information; experimental part, p. 1540 - 1545 (2009/12/25)
We recently discovered the isoform selective RARβ2 ligand 4′-octyl-4-biphenylcarboxylic acid (3, AC-55649). Although 3 is highly potent at RARβ2 and displays excellent selectivity, solubility issues make it unsuitable for drug development. Herein we descr
